1.やさしい
Infliximab and adalimumab are biological drugs that block:
- AHistamine H1 receptors in the skin and airways
- BVitamin K recycling
- CTumour necrosis factor-alpha (TNF-alpha)
- DInsulin receptors
2.やさしい
大部分の薬を主に代謝する臓器はどれですか?
- A肝臓
- B腎臓
- C脾臓
- D肺
3.やさしい
In the United States, what is a "boxed warning" (black box warning) on a drug label?
- AA sign that the drug must be stored in a dark box
- BA note that the drug is available without prescription
- CA label showing that the drug is a controlled substance with abuse potential
- DThe strongest FDA warning about a serious or life-threatening risk
4.ふつう
While giving medicines, a patient says, "That pill looks different from the one I usually take." What should the nurse do?
- AStop and recheck the order and the medicine before giving it
- BExplain that only the staff decide which medicines are given
- CReassure the patient and give the pill anyway
- DGive the pill and check the chart afterwards
5.ふつう
Which assessment is most important during IV mannitol therapy?
- AUrine output, electrolytes and signs of fluid overload
- BLiver enzymes and signs of jaundice
- CPlatelet count and signs of bleeding
- DBlood glucose before meals and signs of hypoglycaemia
6.ふつう
特に若い人で、メトクロプラミドに典型的な副作用はどれですか?
- A低血糖
- B急性ジストニアなどの錐体外路性の運動障害
- C空咳
- D重い便秘
7.むずかしい
A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?
- A25 mL/h
- B4 mL/h
- C15 mL/h
- D150 mL/h
8.むずかしい
狭心症に硝酸薬を使っている患者にシルデナフィルが禁忌なのはなぜですか?
- A硝酸薬が肝臓でのシルデナフィルの代謝を遮断するから
- B組み合わせると危険な高カリウム血症を起こすから
- Cシルデナフィルが血管内で硝酸薬から一酸化窒素への変換を遮断するから
- Dどちらも血管平滑筋の cGMP を上げ、重い低血圧を起こしうるから
解答
- 1. C · Tumour necrosis factor-alpha (TNF-alpha)
- 2. A · 肝臓
- 3. D · The strongest FDA warning about a serious or life-threatening risk
- 4. A · Stop and recheck the order and the medicine before giving it
- 5. A · Urine output, electrolytes and signs of fluid overload
- 6. B · 急性ジストニアなどの錐体外路性の運動障害
- 7. C · 15 mL/h
- 8. D · どちらも血管平滑筋の cGMP を上げ、重い低血圧を起こしうるから
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