解答つき薬理学ワークシート

How does rasagiline help in Parkinson's disease?

1. AIt blocks acetylcholine receptors in the gut
2. BIt is converted directly into dopamine inside brain neurones
3. CIt blocks dopamine receptors in the brain
4. DIt inhibits MAO-B, so brain dopamine is broken down more slowly

Buspirone is used mainly to treat:

1. ASevere pain
2. BPanic attacks needing immediate relief
3. CGeneralised anxiety disorder
4. DAcute alcohol withdrawal

Donepezil, used in Alzheimer's disease, belongs to which class?

1. ASelective serotonin reuptake inhibitors
2. BDopamine agonists
3. CBenzodiazepines
4. DAcetylcholinesterase inhibitors

Why are benzodiazepines used with great caution in older people?

1. AThey are not absorbed from the gut after age 65
2. BThey cause permanent hearing loss in older people
3. CThey cause severe high blood pressure in older people
4. DThey raise the risk of confusion, falls and fractures

A patient takes theophylline for COPD. Which advice is most important?

1. ATake extra doses when short of breath
2. BAvoid potassium-rich foods such as bananas
3. CLimit coffee, tea and cola, because caffeine adds to the side effects
4. DDrink plenty of grapefruit juice each morning to improve absorption

旧来の MAO 阻害薬を服用している患者は、チラミンの多い食品について注意を受けます。何が起こりうるのですか？

1. A突然の腎不全
2. B重い低血糖
3. C高血圧クリーゼ
4. Dアレルギー性の発疹

長時間作用型の硝酸薬を使っている患者に、毎日数時間の硝酸薬のない時間を設けるよう勧めるのはなぜですか？

1. A脂肪組織への硝酸薬の蓄積を避けるため
2. B出血のリスクを減らすため
3. C硝酸薬への耐性を防ぐため
4. D肝臓を毒性から回復させるため

A patient on heparin for 7 days has a platelet count that has fallen by more than half, and a new leg vein thrombosis. What is the most likely cause and the key action?

1. AHeparin-induced thrombocytopenia; stop all heparin
2. BVitamin K deficiency; give vitamin K and continue heparin
3. CWarfarin skin necrosis; switch from heparin to warfarin at once
4. DNormal dilution of platelets; continue and recheck in a week