1.やさしい
Fibrates such as fenofibrate mainly lower which blood lipid?
- ALipoprotein(a) only
- BHDL cholesterol
- CBile acids
- DTriglycerides
2.やさしい
Which drug is the antidote for magnesium sulfate toxicity?
- APotassium chloride
- BProtamine sulfate
- CNaloxone
- DCalcium gluconate
3.やさしい
On the WHO analgesic ladder, which drugs form the first step?
- AStrong opioids such as morphine given intravenously
- BWeak opioids such as codeine or tramadol, used on their own
- CNon-opioids such as paracetamol and NSAIDs
- DLocal anaesthetic nerve blocks for all patients
4.ふつう
Which patient should usually not use the combined oral contraceptive pill?
- AA 25-year-old woman with heavy periods
- BA 30-year-old non-smoker with no medical problems
- CA 22-year-old non-smoker with acne
- DA 38-year-old woman who smokes 20 cigarettes a day
5.ふつう
A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?
- AHigher blood ammonia with improved appetite
- BTen watery stools a day and a low serum potassium
- CNo bowel movement for three days, with less confusion than before
- DBetter alertness and orientation, with two to three soft stools a day
6.ふつう
A patient with suspected sepsis has blood cultures ordered and a first antibiotic dose due. What should the nurse do?
- ATake the blood cultures first, then give the antibiotic at once
- BGive the antibiotic first, then take blood cultures the next day
- CWait for the culture results before giving any antibiotic
- DGive the antibiotic only if the temperature is above 40 °C (104 °F)
7.むずかしい
A 19-year-old woman is starting isotretinoin for severe acne. Which requirement is most important?
- AWeekly hearing tests and monthly eye examinations during treatment
- BA high-vitamin A diet to boost the effect
- CReliable contraception and pregnancy tests, as it is highly teratogenic
- DTaking the drug only at weekends
8.むずかしい
狭心症に硝酸薬を使っている患者にシルデナフィルが禁忌なのはなぜですか?
- A硝酸薬が肝臓でのシルデナフィルの代謝を遮断するから
- Bシルデナフィルが血管内で硝酸薬から一酸化窒素への変換を遮断するから
- C組み合わせると危険な高カリウム血症を起こすから
- Dどちらも血管平滑筋の cGMP を上げ、重い低血圧を起こしうるから
解答
- 1. D · Triglycerides
- 2. D · Calcium gluconate
- 3. C · Non-opioids such as paracetamol and NSAIDs
- 4. D · A 38-year-old woman who smokes 20 cigarettes a day
- 5. D · Better alertness and orientation, with two to three soft stools a day
- 6. A · Take the blood cultures first, then give the antibiotic at once
- 7. C · Reliable contraception and pregnancy tests, as it is highly teratogenic
- 8. D · どちらも血管平滑筋の cGMP を上げ、重い低血圧を起こしうるから
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