解答つき薬理学ワークシート

What is drug synergism?

1. AA drug loses its effect after repeated doses
2. BTwo drugs together have a greater effect than the sum of each alone
3. CTwo drugs together produce exactly the sum of their separate effects
4. DOne drug cancels out the effect of another drug

アトロピンはどの種類の受容体を遮断しますか？

1. Aβ1 アドレナリン受容体
2. B神経筋接合部のニコチン性受容体
3. Cムスカリン性アセチルコリン受容体
4. Dヒスタミン H1 受容体

急性の喘息発作を和らげるのに使う薬のグループは？

1. Aβ 遮断薬
2. BACE 阻害薬
3. C短時間作用型 β2 刺激薬
4. D抗ヒスタミン薬

A patient with insulin-treated diabetes is found unconscious with very low blood glucose. There is no IV access. Which drug can a trained helper give?

1. AIntramuscular adrenaline
2. BRapid-acting insulin under the skin
3. COral glucose gel poured into the mouth
4. DGlucagon by injection or nasal spray

How should a patient take oral alendronate?

1. AWith plain water on an empty stomach, staying upright for 30 minutes
2. BCrushed into yoghurt with calcium supplements
3. CWith milk at bedtime, then lying down straight away to aid absorption
4. DWith breakfast and coffee to protect the stomach

Sumatriptan is contraindicated in which patient?

1. AA patient with a recent ankle sprain
2. BA patient with iron deficiency anaemia
3. CA patient with coronary artery disease
4. DA patient with mild asthma

コデインは CYP2D6 によってモルヒネに変換されます。CYP2D6 の超高速代謝型（ultra-rapid metaboliser）の患者では何が起こりますか？

1. Aコデインは未変化のまま尿中に排泄される
2. Bコデインは不活性な化合物にだけ変換される
3. Cより多くのモルヒネが作られ、オピオイド中毒のリスクが高まる
4. Dモルヒネがほとんど作られないため、コデインはほとんど鎮痛効果を示さない

Why do infants absorb more of a topical corticosteroid than adults?

1. AThey have more skin area per kilogram and thinner skin
2. BTheir liver changes the cream into a much stronger form
3. CInfants do not absorb topical drugs at all
4. DTheir skin contains no blood vessels