解答つき薬理学ワークシート

Which vasopressor is usually first-line for septic shock that persists after fluids?

1. AAdenosine
2. BIsoprenaline (isoproterenol)
3. CGlyceryl trinitrate
4. DNoradrenaline (norepinephrine)

What is a "broad-spectrum" antibiotic?

1. AOne that also treats viral and fungal infections
2. BOne that is taken for a long time at low dose to prevent any infection
3. COne that acts against many Gram-positive and Gram-negative bacteria
4. DOne that is given only intravenously in hospital

Which signs are typical of hypoglycaemia?

1. AThirst, frequent urination and warm, dry, flushed skin
2. BSweating, shakiness, a fast heart rate and confusion
3. CFruity breath with deep, rapid breathing
4. DA slow pulse, constipation and weight gain

Sumatriptan is contraindicated in which patient?

1. AA patient with a recent ankle sprain
2. BA patient with iron deficiency anaemia
3. CA patient with coronary artery disease
4. DA patient with mild asthma

クロピドグレルはどのように血小板凝集を抑えますか？

1. Aアンチトロンビンを活性化する
2. B血小板の COX-1 を阻害する
3. C血小板の ADP 受容体 P2Y12 を遮断する
4. D糖タンパク質 IIb/IIIa 受容体を直接遮断する

アピキサバンとリバーロキサバンは、何を直接阻害する抗凝固薬ですか？

1. A第 Xa 因子
2. Bトロンビン
3. C血小板の P2Y12 受容体
4. Dビタミン K エポキシド還元酵素

A patient on rifampicin, isoniazid, pyrazinamide and ethambutol develops a painful swollen big toe. Which drug is most likely responsible?

1. AEthambutol
2. BRifampicin
3. CIsoniazid
4. DPyrazinamide

A patient with heart failure on furosemide is also given metolazone, a thiazide-like diuretic. Which risk increases most?

1. ASevere hypokalaemia, hyponatraemia and dehydration
2. BHypoglycaemia and weight gain
3. CSevere hypertension, tachycardia and fluid retention
4. DHyperkalaemia and fluid overload