1.やさしい
What does pharmacokinetics describe?
- AWhat a drug does to the body: its effects, receptors and mechanisms of action
- BHow drugs are manufactured and packaged
- CWhat the body does to a drug: absorption, distribution, metabolism and excretion
- DHow the price of a drug is set
2.やさしい
What is a "high-alert medication"?
- AA new drug during its first year on the market
- BA drug that causes more serious harm when used in error
- CA drug that is expensive and must be kept in a locked cupboard
- DAny drug that is given by the intravenous or intramuscular route
3.やさしい
Celecoxib selectively inhibits which enzyme?
- ACyclo-oxygenase-1 (COX-1)
- BCyclo-oxygenase-2 (COX-2)
- CPhospholipase A2
- DLipoxygenase
4.ふつう
A malnourished patient with alcohol dependence needs IV glucose. Which vitamin should be given before or with it?
- AVitamin C
- BVitamin K (phytomenadione)
- CThiamine (vitamin B1)
- DVitamin D
5.ふつう
Which technique is correct when giving subcutaneous enoxaparin from a prefilled syringe?
- AExpel the air bubble from the syringe first, then inject into the deltoid muscle
- BInject into the abdomen away from the navel and do not rub the site afterwards
- CInject into a vein on the back of the hand
- DMassage the site well for one minute after the injection
6.ふつう
A parent will give a liquid medicine to a child at home. Which advice is safest?
- AUse the oral syringe or measuring cup supplied with it
- BMix the dose into a full bottle of milk
- CUse any kitchen teaspoon
- DEstimate the dose by pouring the liquid into a small cup
7.むずかしい
During an alteplase infusion for acute ischaemic stroke, the patient develops a sudden severe headache and her level of consciousness falls. What is the nurse's first action?
- AStop the alteplase infusion and notify the provider urgently
- BGive paracetamol for the headache and continue the infusion
- CSlow the infusion to half the rate and recheck in 30 minutes
- DGive a bolus of heparin to prevent a new clot
8.むずかしい
腎不全のためにある薬のクリアランスが半分に下がり、分布容積は変わりません。半減期はどうなりますか?
- A4 倍になる
- B変わらない
- C半分になる
- D2 倍になる
解答
- 1. C · What the body does to a drug: absorption, distribution, metabolism and excretion
- 2. B · A drug that causes more serious harm when used in error
- 3. B · Cyclo-oxygenase-2 (COX-2)
- 4. C · Thiamine (vitamin B1)
- 5. B · Inject into the abdomen away from the navel and do not rub the site afterwards
- 6. A · Use the oral syringe or measuring cup supplied with it
- 7. A · Stop the alteplase infusion and notify the provider urgently
- 8. D · 2 倍になる
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