1.やさしい
Propofol is mainly used for:
- AInducing and maintaining anaesthesia, and ICU sedation
- BPain relief after surgery on the ward
- CTreating nausea after chemotherapy
- DLong-term treatment of epilepsy at home by mouth
2.やさしい
Why is vitamin K given to newborn babies?
- ATo protect against hepatitis B
- BTo prevent neonatal jaundice in the first week
- CTo improve weight gain
- DTo prevent vitamin K deficiency bleeding
3.やさしい
Mannitol is an osmotic diuretic used mainly to:
- AReduce raised intracranial pressure
- BPrevent blood clots
- CRaise serum potassium
- DTreat high blood pressure long term
4.ふつう
A patient with suspected sepsis has blood cultures ordered and a first antibiotic dose due. What should the nurse do?
- AWait for the culture results before giving any antibiotic
- BGive the antibiotic only if the temperature is above 40 °C (104 °F)
- CGive the antibiotic first, then take blood cultures the next day
- DTake the blood cultures first, then give the antibiotic at once
5.ふつう
ある薬が肝酵素 CYP3A4 を阻害します。主に CYP3A4 で代謝される 2 つ目の薬はどうなる可能性がありますか?
- A腎臓からより速く排泄される
- B血中濃度が下がるので、通常の用量では効かなくなることがある
- C酵素は他の薬に影響しないので変化はない
- D血中濃度が上がり、副作用のリスクが高まる
6.ふつう
1000 mL of IV fluid is to be given over 8 hours with a pump. What rate should be set?
- A125 mL/h
- B250 mL/h
- C100 mL/h
- D80 mL/h
7.むずかしい
Why are oral liquid medicines drawn up in dedicated oral or enteral syringes that do not fit IV connectors?
- ATo keep the medicine sterile for injection
- BTo prevent oral liquids being given intravenously by mistake
- CTo make the oral dose more accurate than a dose given through an IV syringe
- DBecause IV syringes cannot hold liquids
8.むずかしい
A man taking spironolactone for heart failure develops painful breast enlargement. Which change may be considered?
- AAdding testosterone injections
- BSwitching to potassium chloride tablets
- CSwitching to eplerenone, which has fewer anti-androgen effects
- DDoubling the spironolactone dose to overcome the side effect
解答
- 1. A · Inducing and maintaining anaesthesia, and ICU sedation
- 2. D · To prevent vitamin K deficiency bleeding
- 3. A · Reduce raised intracranial pressure
- 4. D · Take the blood cultures first, then give the antibiotic at once
- 5. D · 血中濃度が上がり、副作用のリスクが高まる
- 6. A · 125 mL/h
- 7. B · To prevent oral liquids being given intravenously by mistake
- 8. C · Switching to eplerenone, which has fewer anti-androgen effects
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