Užduočių lapas tema Farmakologija su atsakymais

What is a prodrug?

1. AA drug that has passed all clinical trials
2. BA drug that is inactive until the body converts it into its active form
3. CA drug that is given before surgery
4. DA drug that prevents or reverses the effect of another drug in the body

Benzodiazepinai, pvz., diazepamas, veikia stiprindami kurio neuromediatoriaus poveikį?

1. ASerotonino
2. BNoradrenalino
3. CGlutamato
4. DGABA

How does tramadol relieve pain?

1. ABlocking COX enzymes in the periphery
2. BBlocking sodium channels in peripheral nerves
3. CAntagonising NMDA receptors in the spinal cord and blocking sodium channels
4. DWeak opioid agonism plus inhibiting the reuptake of serotonin and noradrenaline

How is adenosine given for supraventricular tachycardia?

1. AAs a slow infusion over one hour
2. BAs a tablet under the tongue
3. CAs an intramuscular injection into the outer thigh muscle
4. DAs a rapid IV push followed by a fast saline flush

Senesniuosius MAO inhibitorius vartojantys pacientai įspėjami dėl tiramino turtingo maisto. Kas gali nutikti?

1. AAlerginis bėrimas
2. BStaigus inkstų nepakankamumas
3. CHipertenzinė krizė
4. DSunki hipoglikemija

Which signs suggest early lithium toxicity?

1. ADiarrhoea, vomiting, coarse tremor and drowsiness
2. BPinpoint pupils and slow breathing
3. CVery high blood pressure and a severe headache
4. DHair loss and dark urine only

Before starting long-term bisphosphonate treatment, a patient is advised to have a dental check-up. Why?

1. AThey are linked to osteonecrosis of the jaw after dental surgery
2. BBisphosphonates dissolve tooth enamel within weeks
3. CBisphosphonates cause severe gum overgrowth
4. DBisphosphonates stain the teeth black if taken for many years

Nekonkurencinis (negrįžtamas) antagonistas keičia dozės ir atsako kreivę:

1. APadarydamas kreivę statesnę be kitų pokyčių
2. BPaslinkdamas kreivę į dešinę esant tam pačiam maksimumui
3. CPaslinkdamas kreivę į kairę
4. DSumažindamas didžiausią atsaką