Užduočių lapas tema Farmakologija su atsakymais

Desmopressin is a synthetic analogue of which hormone?

1. AAldosterone
2. BAntidiuretic hormone (vasopressin)
3. CInsulin
4. DOxytocin, the hormone of labour

Kokio tipo receptorius blokuoja atropinas?

1. ABeta-1 adrenerginius receptorius
2. BMuskarininius acetilcholino receptorius
3. CHistamino H1 receptorius
4. DNikotininius receptorius nervo ir raumens sinapsėje

Benzodiazepinai, pvz., diazepamas, veikia stiprindami kurio neuromediatoriaus poveikį?

1. ANoradrenalino
2. BGlutamato
3. CSerotonino
4. DGABA

Besides lithium levels, which blood tests are monitored in long-term lithium treatment?

1. ATroponin and CK-MB
2. BKidney function and thyroid function
3. CLiver enzymes, serum amylase and lipase
4. DINR and fibrinogen

Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?

1. AThis gene variant makes carbamazepine ineffective
2. BIt greatly raises the risk of Stevens–Johnson syndrome
3. CThis gene variant causes carbamazepine to raise blood glucose
4. DThis gene variant speeds up the kidney excretion of carbamazepine

Which antihypertensive class can raise blood glucose and uric acid levels, sometimes triggering gout?

1. AAlpha-1 blockers
2. BThiazide diuretics
3. CAngiotensin II receptor blockers
4. DACE inhibitors

Why is the TPMT enzyme often tested before azathioprine is started?

1. ATPMT is needed to absorb azathioprine from the gut
2. BLow TPMT activity causes toxic levels and marrow suppression
3. CTPMT testing shows whether the patient has tuberculosis
4. DHigh TPMT activity causes an allergic reaction to azathioprine

A patient who takes clonidine stopped it suddenly two days ago. He is now agitated, has a headache and his blood pressure is very high. What is the most likely explanation?

1. ANormal variation unrelated to the medication
2. BAn allergic reaction to clonidine
3. CRebound hypertension from abrupt clonidine withdrawal
4. DClonidine toxicity due to slow excretion by the kidneys