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Vardas: ____________________ Data: ____________
1.Lengvas
Kuri iš šių yra tipinė vaistų metabolizmo II fazės (konjugacijos) reakcija?
ARedukcija
BGliukuronidacija
COksidacija
DHidrolizė
2.Lengvas
Chlordiazepoxide is commonly used to manage:
ABipolar mania
BAlcohol withdrawal
COpioid overdose
DMigraine prevention
3.Lengvas
What does pharmacokinetics describe?
AWhat a drug does to the body: its effects, receptors and mechanisms of action
BHow the price of a drug is set
CHow drugs are manufactured and packaged
DWhat the body does to a drug: absorption, distribution, metabolism and excretion
4.Vidutinis
A patient with insulin-treated diabetes is found unconscious with very low blood glucose. There is no IV access. Which drug can a trained helper give?
AIntramuscular adrenaline
BGlucagon by injection or nasal spray
CRapid-acting insulin under the skin
DOral glucose gel poured into the mouth
5.Vidutinis
A patient takes regular paracetamol (acetaminophen) at home. Which teaching point best prevents accidental overdose?
ACheck cold and flu remedies, as many also contain paracetamol
BTake an extra dose if the first one does not work within 10 minutes
CUse paracetamol only on an empty stomach
DTake paracetamol with alcohol to improve absorption
6.Vidutinis
Before starting a TNF-alpha inhibitor such as adalimumab, which test is required?
AA glucose tolerance test
BScreening for latent tuberculosis
CAn echocardiogram in every patient
DA bone density scan
7.Sunkus
A patient with heart failure on furosemide is also given metolazone, a thiazide-like diuretic. Which risk increases most?
ASevere hypokalaemia, hyponatraemia and dehydration
BHyperkalaemia and fluid overload
CHypoglycaemia and weight gain
DSevere hypertension, tachycardia and fluid retention
8.Sunkus
500 mg dozė į veną sukuria pradinę 10 mg/L koncentraciją plazmoje. Koks pasiskirstymo tūris?
A5 L
B50 L
C500 L
D5000 L
Atsakymai
1. B · Gliukuronidacija
2. B · Alcohol withdrawal
3. D · What the body does to a drug: absorption, distribution, metabolism and excretion
4. B · Glucagon by injection or nasal spray
5. A · Check cold and flu remedies, as many also contain paracetamol
6. B · Screening for latent tuberculosis
7. A · Severe hypokalaemia, hyponatraemia and dehydration
8. B · 50 L
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