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Nama: ____________________ Tarikh: ____________
1.Mudah
Why is folinic acid (leucovorin) given after high-dose methotrexate?
ATo make methotrexate act faster on the tumour
BTo protect normal cells from methotrexate toxicity
CTo prevent nausea and vomiting after the methotrexate
DTo treat an allergic reaction to methotrexate
2.Mudah
Infliximab and adalimumab are biological drugs that block:
ATumour necrosis factor-alpha (TNF-alpha)
BHistamine H1 receptors in the skin and airways
CVitamin K recycling
DInsulin receptors
3.Mudah
What is the purpose of "Tall Man" lettering, such as hydrOXYzine and hydrALAZINE?
ATo show which drugs are high-alert medications
BTo show which drugs are for children
CTo show the brand name of the drug
DTo reduce confusion between look-alike drug names
4.Sederhana
Which patient should usually not use the combined oral contraceptive pill?
AA 30-year-old non-smoker with no medical problems
BA 25-year-old woman with heavy periods
CA 22-year-old non-smoker with acne
DA 38-year-old woman who smokes 20 cigarettes a day
5.Sederhana
A patient with a fentanyl patch is given home-care advice. Which instruction is correct?
ACut the patch in half if the pain is mild
BApply each new patch over the same skin area
CThrow used patches loose into the household bin with the packaging
DAvoid heating pads, hot baths and saunas over or near the patch
6.Sederhana
Bagaimanakah heparin menghasilkan kesan antikoagulan?
AIa menyekat sintesis faktor pembekuan dalam hati yang bergantung pada vitamin K
BIa merencat COX-1 platelet secara tak berbalik
CIa memecahkan fibrin dalam bekuan sedia ada
DIa meningkatkan antitrombin, yang menyahaktifkan trombin dan faktor Xa
7.Sukar
A patient has a serum potassium of 7.0 mmol/L (mEq/L) and peaked T waves on the ECG. Which drug is given first to protect the heart?
AOral potassium chloride
BOral sodium polystyrene sulfonate
CIntravenous furosemide
DIntravenous calcium gluconate
8.Sukar
A patient on valproate becomes lethargic, starts vomiting and develops jaundice. Which adverse effect should be suspected first?
ANormal start-up side effects
BKidney stones
CLiver toxicity
DHypothyroidism
Kunci jawapan
1. B · To protect normal cells from methotrexate toxicity
2. A · Tumour necrosis factor-alpha (TNF-alpha)
3. D · To reduce confusion between look-alike drug names
4. D · A 38-year-old woman who smokes 20 cigarettes a day
5. D · Avoid heating pads, hot baths and saunas over or near the patch
6. D · Ia meningkatkan antitrombin, yang menyahaktifkan trombin dan faktor Xa
7. D · Intravenous calcium gluconate
8. C · Liver toxicity
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