Lembaran kerja Farmakologi dengan jawapan

Mengapakah aspirin dos rendah diberi kepada sesetengah orang dengan penyakit jantung?

1. AUntuk mengurangkan agregasi platelet dan mencegah bekuan
2. BUntuk menurunkan paras kolesterol darah dan menstabilkan plak
3. CUntuk melegakan sakit dada serta-merta
4. DUntuk memperlahankan kadar jantung

Organ manakah yang terutamanya bertanggungjawab memetabolismekan kebanyakan ubat?

1. ABuah pinggang
2. BParu-paru
3. CHati
4. DLimpa

Celecoxib selectively inhibits which enzyme?

1. ALipoxygenase
2. BCyclo-oxygenase-2 (COX-2)
3. CCyclo-oxygenase-1 (COX-1)
4. DPhospholipase A2

Which antihypertensive class can raise blood glucose and uric acid levels, sometimes triggering gout?

1. AAlpha-1 blockers
2. BThiazide diuretics
3. CACE inhibitors
4. DAngiotensin II receptor blockers

A patient takes theophylline for COPD. Which advice is most important?

1. ALimit coffee, tea and cola, because caffeine adds to the side effects
2. BAvoid potassium-rich foods such as bananas
3. CTake extra doses when short of breath
4. DDrink plenty of grapefruit juice each morning to improve absorption

Apakah kesan buruk paling penting sulfonilurea seperti gliklazid?

1. AAsidosis laktik
2. BBatuk kering
3. CHiperkalemia
4. DHipoglisemia

A malnourished patient with low serum albumin shows nystagmus and unsteady gait. Her total phenytoin level is within range. What is the most likely explanation?

1. ALow albumin makes phenytoin bind more tightly, so the drug is less active
2. BLow albumin speeds up phenytoin metabolism
3. CThe total level is high, but the laboratory is wrong
4. DMore phenytoin is unbound when albumin is low, so free levels rise

A man on long-term testosterone therapy has a rising haematocrit. Why is this important?

1. ATestosterone raises red cell production, increasing clot risk
2. BA high haematocrit shows that the testosterone is not being absorbed
3. CIt means the testosterone dose is too low
4. DIt is a sign of liver failure caused by testosterone