Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

Why is folinic acid (leucovorin) given after high-dose methotrexate?

  1. ATo make methotrexate act faster on the tumour
  2. BTo protect normal cells from methotrexate toxicity
  3. CTo prevent nausea and vomiting after the methotrexate
  4. DTo treat an allergic reaction to methotrexate
2.Makkelijk

Infliximab and adalimumab are biological drugs that block:

  1. ATumour necrosis factor-alpha (TNF-alpha)
  2. BHistamine H1 receptors in the skin and airways
  3. CVitamin K recycling
  4. DInsulin receptors
3.Makkelijk

What is the purpose of "Tall Man" lettering, such as hydrOXYzine and hydrALAZINE?

  1. ATo show which drugs are high-alert medications
  2. BTo show which drugs are for children
  3. CTo show the brand name of the drug
  4. DTo reduce confusion between look-alike drug names
4.Gemiddeld

Which patient should usually not use the combined oral contraceptive pill?

  1. AA 30-year-old non-smoker with no medical problems
  2. BA 25-year-old woman with heavy periods
  3. CA 22-year-old non-smoker with acne
  4. DA 38-year-old woman who smokes 20 cigarettes a day
5.Gemiddeld

A patient with a fentanyl patch is given home-care advice. Which instruction is correct?

  1. ACut the patch in half if the pain is mild
  2. BApply each new patch over the same skin area
  3. CThrow used patches loose into the household bin with the packaging
  4. DAvoid heating pads, hot baths and saunas over or near the patch
6.Gemiddeld

Hoe geeft heparine zijn antistollende effect?

  1. AHet blokkeert in de lever de vitamine K-afhankelijke synthese van stollingsfactoren
  2. BHet remt COX-1 in bloedplaatjes onomkeerbaar
  3. CHet breekt fibrine in bestaande stolsels af
  4. DHet versterkt antitrombine, dat trombine en factor Xa inactiveert
7.Moeilijk

A patient has a serum potassium of 7,0 mmol/L (mEq/L) and peaked T waves on the ECG. Which drug is given first to protect the heart?

  1. AOral potassium chloride
  2. BOral sodium polystyrene sulfonate
  3. CIntravenous furosemide
  4. DIntravenous calcium gluconate
8.Moeilijk

A patient on valproate becomes lethargic, starts vomiting and develops jaundice. Which adverse effect should be suspected first?

  1. ANormal start-up side effects
  2. BKidney stones
  3. CLiver toxicity
  4. DHypothyroidism

Antwoordenblad

  1. 1. B · To protect normal cells from methotrexate toxicity
  2. 2. A · Tumour necrosis factor-alpha (TNF-alpha)
  3. 3. D · To reduce confusion between look-alike drug names
  4. 4. D · A 38-year-old woman who smokes 20 cigarettes a day
  5. 5. D · Avoid heating pads, hot baths and saunas over or near the patch
  6. 6. D · Het versterkt antitrombine, dat trombine en factor Xa inactiveert
  7. 7. D · Intravenous calcium gluconate
  8. 8. C · Liver toxicity

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