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Naam: ____________________ Datum: ____________
1.Makkelijk
What is enzyme induction?
AA drug causes an allergic reaction to enzymes
BA drug blocks liver enzymes, so other drugs build up in the blood
CA drug speeds up liver enzymes, so other drugs are broken down faster
DA drug is converted into an enzyme in the body
2.Makkelijk
What is a "high-alert medication"?
AA drug that is expensive and must be kept in a locked cupboard
BAny drug that is given by the intravenous or intramuscular route
CA drug that causes more serious harm when used in error
DA new drug during its first year on the market
3.Makkelijk
What is drug synergism?
AA drug loses its effect after repeated doses
BTwo drugs together produce exactly the sum of their separate effects
CTwo drugs together have a greater effect than the sum of each alone
DOne drug cancels out the effect of another drug
4.Gemiddeld
Hoe geeft heparine zijn antistollende effect?
AHet remt COX-1 in bloedplaatjes onomkeerbaar
BHet breekt fibrine in bestaande stolsels af
CHet versterkt antitrombine, dat trombine en factor Xa inactiveert
DHet blokkeert in de lever de vitamine K-afhankelijke synthese van stollingsfactoren
5.Gemiddeld
How should oral potassium chloride tablets be taken?
AOn an empty stomach with only a small sip of water, then lie down
BWith food and plenty of water, swallowed whole if slow-release
CCrushed and dissolved under the tongue
DLying down straight after the dose
6.Gemiddeld
A transplant patient takes tacrolimus. Which monitoring is most important?
AThyroid function and bone density
BBlood drug levels and kidney function
CSerum amylase
DPeak expiratory flow
7.Moeilijk
A patient who has taken lorazepam daily for many months stops it suddenly. Which serious complication may follow?
APinpoint pupils and coma
BSevere bradycardia
CWithdrawal seizures
DProfound respiratory depression
8.Moeilijk
Why should a dose never be written as "5,0 mg" on a medication order?
AThe pharmacy cannot supply doses that contain a decimal point
BIt is too precise for most drugs
CIt means the dose must be given five times
DThe decimal point may be missed, and the dose read as 50 mg
Antwoordenblad
1. C · A drug speeds up liver enzymes, so other drugs are broken down faster
2. C · A drug that causes more serious harm when used in error
3. C · Two drugs together have a greater effect than the sum of each alone
4. C · Het versterkt antitrombine, dat trombine en factor Xa inactiveert
5. B · With food and plenty of water, swallowed whole if slow-release
6. B · Blood drug levels and kidney function
7. C · Withdrawal seizures
8. D · The decimal point may be missed, and the dose read as 50 mg
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