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Naam: ____________________ Datum: ____________
1.Makkelijk
What does the combined oral contraceptive pill contain?
ATestosterone and an oestrogen
BAn oestrogen and a progestogen
CA progestogen only
DOxytocin and a progestogen
2.Makkelijk
Welk type receptor blokkeert atropine?
ABèta-1-adrenerge receptoren
BNicotinerge receptoren op de neuromusculaire overgang
CMuscarinerge acetylcholinereceptoren
DHistamine-H1-receptoren
3.Makkelijk
Donepezil, used in Alzheimer's disease, belongs to which class?
ABenzodiazepines
BDopamine agonists
CSelective serotonin reuptake inhibitors
DAcetylcholinesterase inhibitors
4.Gemiddeld
A patient with heart failure starts furosemide. Which self-monitoring instruction is most useful?
AMeasure the temperature twice a day and record it in a diary
BCount the respiratory rate each evening
CWeigh daily at the same time on the same scales
DCheck the blood glucose before every meal
5.Gemiddeld
Methylergometrine (methylergonovine) is prescribed for postpartum bleeding. Which finding would make the nurse withhold it and check with the prescriber?
AHeart rate of 88 per minute
BHaemoglobin slightly below normal
CBlood pressure of 160/105 mmHg
DTemperature of 37,2 °C (99 °F)
6.Gemiddeld
A nurse has a needlestick injury from a patient with HIV. When should post-exposure prophylaxis start?
AAs soon as possible, and within 72 hours at the latest
BAfter one week, when the risk of infection is clearer
COnly after the nurse's HIV test turns positive
DOnly if the patient's viral load is above a set level
7.Moeilijk
A patient with severe liver cirrhosis takes oral propranolol, a drug with a high first-pass metabolism. What effect is expected?
AThe first-pass effect increases, so the drug becomes inactive
BThe drug is excreted faster by the kidney, so it works for a shorter time
CMore drug reaches the circulation, so a lower dose may be needed
DLess drug is absorbed from the gut, so a higher dose is needed
8.Moeilijk
Why is pethidine (meperidine) avoided in older people and in kidney impairment?
AIt has no pain-relieving effect in older people
BIt causes severe hypoglycaemia in these groups
CIts metabolite norpethidine builds up and can cause seizures
DIt is not absorbed from the gut when kidney function is poor
Antwoordenblad
1. B · An oestrogen and a progestogen
2. C · Muscarinerge acetylcholinereceptoren
3. D · Acetylcholinesterase inhibitors
4. C · Weigh daily at the same time on the same scales
5. C · Blood pressure of 160/105 mmHg
6. A · As soon as possible, and within 72 hours at the latest
7. C · More drug reaches the circulation, so a lower dose may be needed
8. C · Its metabolite norpethidine builds up and can cause seizures
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