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Naam: ____________________ Datum: ____________
1.Makkelijk
How does rasagiline help in Parkinson's disease?
AIt blocks dopamine receptors in the brain
BIt inhibits MAO-B, so brain dopamine is broken down more slowly
CIt blocks acetylcholine receptors in the gut
DIt is converted directly into dopamine inside brain neurones
2.Makkelijk
Which adverse effect is most common with colchicine?
AWeight gain and swelling
BConstipation and dry mouth
CDiarrhoea, nausea and vomiting
DDrowsiness and slow breathing
3.Makkelijk
What does "bacteriostatic" mean?
AThe drug stops bacteria multiplying without killing them directly
BThe drug kills viruses as well as bacteria
CThe drug kills bacteria directly by breaking down their cell wall
DThe drug prevents the patient's immune response
4.Gemiddeld
A patient takes cholestyramine. How should other oral medicines be timed?
ATiming does not matter, as cholestyramine is not absorbed
BTake them all at the same time as cholestyramine
CMix them into the cholestyramine drink so they are taken together
DTake them 1 hour before or several hours after cholestyramine
5.Gemiddeld
Waarom mogen langdurig gebruikte orale corticosteroïden niet plotseling worden gestopt?
ADe bijnieren zijn onderdrukt en maken mogelijk niet genoeg cortisol
BStoppen veroorzaakt een plotselinge stijging van de bloedglucose
CHet middel vormt bij stoppen giftige metabolieten
DHet immuunsysteem zou direct de lever en de bijnieren aanvallen
6.Gemiddeld
Why are many drugs started at lower doses in older adults?
ALower doses are cheaper for older patients
BOlder adults always weigh more than younger adults, so drugs last longer
CKidney and liver clearance often decline, and sensitivity to drugs increases
DOlder adults absorb no drugs from the stomach
7.Moeilijk
A patient who has had several courses of bleomycin develops a dry cough and worsening breathlessness. What should the nurse suspect?
AHeart failure from bleomycin
BPulmonary fibrosis from bleomycin
CAsthma caused by anxiety
DA normal effect that will pass in a day
8.Moeilijk
Why is vancomycin given by mouth, not intravenously, for Clostridioides difficile infection?
AOral vancomycin is not absorbed, so it reaches high levels in the colon
BIntravenous vancomycin causes C. difficile infection
CThe oral form is cheaper but has the same effect as IV
DOral vancomycin is absorbed into the blood better than IV vancomycin
Antwoordenblad
1. B · It inhibits MAO-B, so brain dopamine is broken down more slowly
2. C · Diarrhoea, nausea and vomiting
3. A · The drug stops bacteria multiplying without killing them directly
4. D · Take them 1 hour before or several hours after cholestyramine
5. A · De bijnieren zijn onderdrukt en maken mogelijk niet genoeg cortisol
6. C · Kidney and liver clearance often decline, and sensitivity to drugs increases
7. B · Pulmonary fibrosis from bleomycin
8. A · Oral vancomycin is not absorbed, so it reaches high levels in the colon
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