Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

Which of these is a second-generation (atypical) antipsychotic?

  1. AChlorpromazine
  2. BHaloperidol
  3. CFluphenazine
  4. DOlanzapine
2.Makkelijk

Which drug is an antidote for methanol or ethylene glycol (antifreeze) poisoning?

  1. ANaloxone
  2. BFomepizole
  3. CFlumazenil
  4. DAtropine
3.Makkelijk

Welke hiervan is een typische fase II-reactie (conjugatie) in het geneesmiddelmetabolisme?

  1. AHydrolyse
  2. BReductie
  3. CGlucuronidering
  4. DOxidatie
4.Gemiddeld

A person who has never been vaccinated against tetanus has a deep, dirty wound. What is usually given?

  1. ANo treatment unless symptoms appear
  2. BTetanus vaccine only, after the wound heals
  3. CTetanus vaccine and tetanus immunoglobulin
  4. DOral antibiotics only
5.Gemiddeld

How does sucralfate help a peptic ulcer heal?

  1. AIt forms a protective coating over the ulcer base
  2. BIt blocks histamine H2 receptors in the stomach
  3. CIt kills Helicobacter pylori directly
  4. DIt neutralises acid by releasing bicarbonate
6.Gemiddeld

A patient taking levodopa finds that the drug works poorly after large meals. Which advice is most appropriate?

  1. ADouble the dose after each meal
  2. BTake the drug only at bedtime
  3. CAvoid taking doses at the same time as high-protein meals
  4. DTake every dose with a large glass of milk and a protein snack
7.Moeilijk

A patient taking co-trimoxazole develops fever, a spreading blistering rash and painful mouth sores. What is the most likely diagnosis?

  1. ASunburn caused by the drug; advise sunscreen only
  2. BA mild rash that will settle; continue the drug and give moisturiser
  3. CStevens–Johnson syndrome; stop the drug and get urgent medical care
  4. DOral thrush; start an antifungal and continue the antibiotic
8.Moeilijk

A patient has received a sodium nitroprusside infusion for several days. He becomes confused and develops a metabolic acidosis. What should be suspected?

  1. AHyperkalaemia from the infusion
  2. BAn allergic reaction to the plastic of the infusion bag
  3. CHypoglycaemia from nitroprusside
  4. DCyanide toxicity from nitroprusside breakdown

Antwoordenblad

  1. 1. D · Olanzapine
  2. 2. B · Fomepizole
  3. 3. C · Glucuronidering
  4. 4. C · Tetanus vaccine and tetanus immunoglobulin
  5. 5. A · It forms a protective coating over the ulcer base
  6. 6. C · Avoid taking doses at the same time as high-protein meals
  7. 7. C · Stevens–Johnson syndrome; stop the drug and get urgent medical care
  8. 8. D · Cyanide toxicity from nitroprusside breakdown

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