Werkblad Farmacologie met antwoorden

What is the most common side effect of first-generation antihistamines such as diphenhydramine?

1. ADiarrhoea
2. BDrowsiness
3. CRaised blood pressure
4. DInsomnia

Which antibiotic group shares the beta-lactam ring with penicillins?

1. AAminoglycosides
2. BMacrolides
3. CTetracyclines
4. DCephalosporins

Methylphenidate, used in ADHD, belongs to which class?

1. ABenzodiazepines
2. BOpioid analgesics
3. CAntipsychotics (dopamine blockers)
4. DCentral nervous system stimulants

How does sucralfate help a peptic ulcer heal?

1. AIt forms a protective coating over the ulcer base
2. BIt neutralises acid by releasing bicarbonate
3. CIt blocks histamine H2 receptors in the stomach
4. DIt kills Helicobacter pylori directly

Waarom verhogen NSAID's zoals ibuprofen het risico op een maagzweer?

1. AZe vermeerderen het aantal Helicobacter pylori-bacteriën in de maag
2. BZe verlagen beschermende prostaglandinen in het maagslijmvlies
3. CZe lossen de slijmlaag direct op
4. DZe verhogen de pH van het maagzuur

Welke bijwerking is typisch voor de calciumantagonist amlodipine?

1. AHyperkaliëmie
2. BEnkeloedeem
3. CBronchospasme
4. DDroge hoest

A patient with myasthenia gravis took extra pyridostigmine doses. She now has increasing weakness, heavy salivation, sweating, small pupils and diarrhoea. What is the most likely cause?

1. AMyasthenic crisis from too little anticholinesterase drug
2. BAn allergic reaction to pyridostigmine
3. CA stroke unrelated to the medication
4. DCholinergic crisis from too much anticholinesterase drug

A patient on heparin for 7 days has a platelet count that has fallen by more than half, and a new leg vein thrombosis. What is the most likely cause and the key action?

1. AWarfarin skin necrosis; switch from heparin to warfarin at once
2. BHeparin-induced thrombocytopenia; stop all heparin
3. CVitamin K deficiency; give vitamin K and continue heparin
4. DNormal dilution of platelets; continue and recheck in a week