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Naam: ____________________ Datum: ____________
1.Makkelijk
Varenicline helps people stop smoking because it:
ABlocks dopamine receptors in the brain completely
BMakes cigarettes taste bitter
CIs a form of nicotine absorbed slowly through the skin
DIs a nicotinic partial agonist that reduces craving and reward
2.Makkelijk
Why is carbidopa combined with levodopa?
AIt converts levodopa into dopamine inside the gut
BIt increases the breakdown of dopamine in the liver
CIt stops levodopa turning into dopamine outside the brain
DIt blocks dopamine receptors to reduce nausea in the brain
3.Makkelijk
Mesalazine (mesalamine) is used mainly to treat:
AUlcerative colitis
BPeptic ulcer
CIrritable bowel syndrome with constipation
DGallstones
4.Gemiddeld
Sumatriptan is contraindicated in which patient?
AA patient with mild asthma
BA patient with coronary artery disease
CA patient with iron deficiency anaemia
DA patient with a recent ankle sprain
5.Gemiddeld
Why is a spacer recommended with a metered-dose inhaler?
AIt doubles the dose of drug released by each puff of the inhaler
BIt turns the inhaler into a nebuliser
CMore drug reaches the lungs and less stays in the mouth
DIt removes the need to shake the inhaler
6.Gemiddeld
Why should NSAIDs be used with caution in some people with asthma?
AThey can trigger bronchospasm in aspirin-sensitive asthma
BThey cause mucus plugs by drying the airways
CThey increase the clearance of salbutamol
DThey block the anti-inflammatory effect of inhaled corticosteroids
7.Moeilijk
Een man van 80 met een vergrote prostaat begint met oxybutynine voor een overactieve blaas. Hij wordt verward en kan niet plassen. Wat is de waarschijnlijkste verklaring?
AOpioïdintoxicatie
BEen allergische reactie op het middel
CAnticholinerge bijwerkingen
DSerotoninesyndroom
8.Moeilijk
Which statement about raloxifene for postmenopausal osteoporosis is correct?
AIt has no effect on the risk of blood clots
BIt acts like oestrogen in all tissues, including the breast, and relieves hot flushes
CIt acts like oestrogen on bone but blocks oestrogen in the breast, and raises clot risk
DIt is a bisphosphonate taken weekly with water
Antwoordenblad
1. D · Is a nicotinic partial agonist that reduces craving and reward
2. C · It stops levodopa turning into dopamine outside the brain
3. A · Ulcerative colitis
4. B · A patient with coronary artery disease
5. C · More drug reaches the lungs and less stays in the mouth
6. A · They can trigger bronchospasm in aspirin-sensitive asthma
7. C · Anticholinerge bijwerkingen
8. C · It acts like oestrogen on bone but blocks oestrogen in the breast, and raises clot risk
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