Werkblad Farmacologie met antwoorden

Which harmless effect of rifampicin should patients be warned about?

1. AWhite spots on the teeth
2. BOrange-red colouring of urine, sweat and tears
3. CBlue colouring of the fingernails and lips
4. DGreen colouring of the stools

What is the normal serum sodium range in adults?

1. A95–105 mmol/L
2. B3,5–5,0 mmol/L
3. C150–165 mmol/L
4. D135–145 mmol/L

What is a prodrug?

1. AA drug that has passed all clinical trials
2. BA drug that is inactive until the body converts it into its active form
3. CA drug that prevents or reverses the effect of another drug in the body
4. DA drug that is given before surgery

Welke bijwerking is typisch voor de calciumantagonist amlodipine?

1. AEnkeloedeem
2. BBronchospasme
3. CHyperkaliëmie
4. DDroge hoest

Why is directly observed therapy (DOT) often used for tuberculosis?

1. APatients with TB cannot swallow tablets
2. BThe drugs work only if a nurse is present
3. CTB drugs must always be given intravenously in hospital
4. DTreatment lasts months, and missed doses cause resistance

How should oral potassium chloride tablets be taken?

1. ACrushed and dissolved under the tongue
2. BWith food and plenty of water, swallowed whole if slow-release
3. COn an empty stomach with only a small sip of water, then lie down
4. DLying down straight after the dose

A man taking doxazosin for hypertension starts sildenafil for erectile dysfunction. What is the main risk?

1. ASevere hypertension and a pounding headache
2. BBronchospasm
3. CHyperkalaemia
4. DSymptomatic low blood pressure and fainting

A patient is switched from oral to intravenous morphine. Why is the IV dose lower than the oral dose?

1. AIV morphine is excreted much more slowly by the kidney than oral morphine
2. BOral morphine has a large first-pass effect, so less reaches the blood
3. CThe oral route causes tolerance faster than the IV route
4. DIV morphine is a stronger chemical form of the drug