Werkblad Farmacologie met antwoorden

Finasteride is used in benign prostatic hyperplasia because it:

1. AKills bacteria in the prostate
2. BInhibits 5-alpha reductase and slowly shrinks the prostate
3. CRelaxes smooth muscle in the prostate within hours of the first dose
4. DIncreases testosterone production

What does the combined oral contraceptive pill contain?

1. ATestosterone and an oestrogen
2. BA progestogen only
3. COxytocin and a progestogen
4. DAn oestrogen and a progestogen

Welk type receptor blokkeert atropine?

1. ABèta-1-adrenerge receptoren
2. BNicotinerge receptoren op de neuromusculaire overgang
3. CHistamine-H1-receptoren
4. DMuscarinerge acetylcholinereceptoren

A nurse has a needlestick injury from a patient with HIV. When should post-exposure prophylaxis start?

1. AOnly if the patient's viral load is above a set level
2. BAfter one week, when the risk of infection is clearer
3. COnly after the nurse's HIV test turns positive
4. DAs soon as possible, and within 72 hours at the latest

A woman taking tamoxifen should report which symptom promptly?

1. AUnusual vaginal bleeding or a painful swollen leg
2. BMild hot flushes, especially at night, in the first months
3. CSlightly dry skin
4. DMild tiredness in the afternoon

1000 mL of IV fluid is to be given over 8 hours with a pump. What rate should be set?

1. A250 mL/h
2. B100 mL/h
3. C80 mL/h
4. D125 mL/h

A patient on long-term prednisolone has been vomiting for two days and could not take her tablets. She is now hypotensive and confused, with low sodium and high potassium. What is the most urgent treatment?

1. AIV hydrocortisone and IV fluids
2. BIV insulin with glucose only
3. COral prednisolone with a glass of water
4. DIV furosemide

A patient on simvastatin is prescribed gemfibrozil. What is the main concern?

1. AA much higher risk of myopathy and rhabdomyolysis
2. BA sharp rise in LDL cholesterol and triglycerides
3. CSevere hypoglycaemia
4. DLoss of all lipid-lowering effect