Werkblad Farmacologie met antwoorden

Gratis printbaar werkblad Farmacologie: 8 opgaven van makkelijk tot tentamenniveau, met antwoordenblad. Print het of sla het op als pdf.

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Naam: ____________________   Datum: ____________

1.Makkelijk

Welke hiervan is een typische fase II-reactie (conjugatie) in het geneesmiddelmetabolisme?

  1. AOxidatie
  2. BReductie
  3. CHydrolyse
  4. DGlucuronidering
2.Makkelijk

On the WHO analgesic ladder, which drugs form the first step?

  1. AStrong opioids such as morphine given intravenously
  2. BLocal anaesthetic nerve blocks for all patients
  3. CWeak opioids such as codeine or tramadol, used on their own
  4. DNon-opioids such as paracetamol and NSAIDs
3.Makkelijk

Tamoxifen is used mainly to treat:

  1. AOestrogen receptor-positive breast cancer
  2. BOsteoarthritis
  3. CType 2 diabetes
  4. DProstate enlargement and prostate cancer in older men
4.Gemiddeld

When should a patient take a once-daily proton pump inhibitor such as omeprazole?

  1. AWith a glass of milk at bedtime, when acid output is highest
  2. BOnly when heartburn is severe
  3. CAbout 30–60 minutes before the first meal of the day
  4. DStraight after a large evening meal
5.Gemiddeld

A patient is due the first dose of IV cefuroxime. Which question is most important before giving it?

  1. A"Have you eaten anything in the last two hours?"
  2. B"Have you taken paracetamol today?"
  3. C"Have you ever had a reaction to penicillin or another antibiotic?"
  4. D"Do you prefer the drip in your left arm or in your right arm?"
6.Gemiddeld

A patient is starting lisinopril. Which rare but serious adverse effect should the nurse teach the patient to report immediately?

  1. AA harmless rash on the palms of the hands
  2. BSwelling of the lips, tongue or face
  3. CDarker skin after exposure to sunlight
  4. DAn increase in appetite in the evening
7.Moeilijk

Why is gentamicin often given once daily instead of in several small doses?

  1. AIt is absorbed slowly from the muscle over 24 hours
  2. BIt has a very long half-life of several days
  3. CIts killing depends on high peak levels, with a post-antibiotic effect
  4. DIts killing depends only on the time the level stays above the MIC
8.Moeilijk

A patient with heart failure on furosemide is also given metolazone, a thiazide-like diuretic. Which risk increases most?

  1. ASevere hypertension, tachycardia and fluid retention
  2. BHypoglycaemia and weight gain
  3. CHyperkalaemia and fluid overload
  4. DSevere hypokalaemia, hyponatraemia and dehydration

Antwoordenblad

  1. 1. D · Glucuronidering
  2. 2. D · Non-opioids such as paracetamol and NSAIDs
  3. 3. A · Oestrogen receptor-positive breast cancer
  4. 4. C · About 30–60 minutes before the first meal of the day
  5. 5. C · "Have you ever had a reaction to penicillin or another antibiotic?"
  6. 6. B · Swelling of the lips, tongue or face
  7. 7. C · Its killing depends on high peak levels, with a post-antibiotic effect
  8. 8. D · Severe hypokalaemia, hyponatraemia and dehydration

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