Werkblad Farmacologie met antwoorden

Loperamide wordt gebruikt voor de behandeling van:

1. AMisselijkheid
2. BDiarree
3. CZuurbranden
4. DObstipatie

Ondansetron wordt vooral gebruikt voor de behandeling van:

1. AMisselijkheid en braken
2. BObstipatie
3. CHoge bloeddruk
4. DBacteriële infecties

Disulfiram is used in alcohol use disorder because it:

1. AReplaces alcohol at its receptors in the brain
2. BCures liver damage caused by alcohol
3. CRemoves alcohol from the blood faster
4. DCauses an unpleasant reaction if alcohol is drunk

Why is simvastatin traditionally taken in the evening?

1. AIt causes too much drowsiness to be taken in the morning
2. BIt must be taken with the largest meal of the day
3. CIt is short-acting, and cholesterol synthesis peaks at night
4. DIt is inactivated by sunlight during the day

How can the absorption of oral iron be improved?

1. ATake it with vitamin C, such as orange juice, on an empty stomach
2. BTake it at the same time as an antacid to protect the stomach
3. CTake it with a cup of strong tea
4. DTake it with a glass of milk

Hoe vermindert clopidogrel de aggregatie van bloedplaatjes?

1. AHet remt COX-1 in bloedplaatjes
2. BHet activeert antitrombine
3. CHet blokkeert de glycoproteïne IIb/IIIa-receptor rechtstreeks
4. DHet blokkeert de P2Y12-receptor voor ADP op bloedplaatjes

A patient has SIADH with mild hyponatraemia and no neurological symptoms. What is usually the first-line treatment?

1. AA rapid bolus of hypertonic saline
2. BFluid restriction
3. CDesmopressin
4. DLarge volumes of IV glucose 5%

A patient is switched from oral to intravenous morphine. Why is the IV dose lower than the oral dose?

1. AOral morphine has a large first-pass effect, so less reaches the blood
2. BIV morphine is a stronger chemical form of the drug
3. CThe oral route causes tolerance faster than the IV route
4. DIV morphine is excreted much more slowly by the kidney than oral morphine