Werkblad Farmacologie met antwoorden

How do second-generation antihistamines such as cetirizine and loratadine differ from older ones?

1. AThey are given only by injection
2. BThey block H2 receptors in the stomach
3. CThey cause much less drowsiness
4. DThey work only on the skin

Where should an adrenaline (epinephrine) auto-injector be given?

1. AInto the outer thigh muscle
2. BUnder the tongue
3. CInto a vein in the arm
4. DInto the abdomen under the skin

Which drug is the antidote for magnesium sulfate toxicity?

1. AProtamine sulfate
2. BNaloxone
3. CPotassium chloride
4. DCalcium gluconate

Which statement about allopurinol is correct?

1. AIt increases uric acid production to flush out crystals
2. BIt lowers uric acid over time and does not relieve the pain of an acute attack
3. CIt is taken only during an acute attack and stopped as soon as the pain settles
4. DIt works within an hour to relieve joint pain

Why is simvastatin traditionally taken in the evening?

1. AIt must be taken with the largest meal of the day
2. BIt is short-acting, and cholesterol synthesis peaks at night
3. CIt is inactivated by sunlight during the day
4. DIt causes too much drowsiness to be taken in the morning

How many micrograms are in 0,5 mg?

1. A5 micrograms
2. B50 micrograms
3. C500 micrograms
4. D5000 micrograms

Bij een middel met eerste-orde-eliminatie zorgt een verdubbeling van de dosis (met hetzelfde interval) ervoor dat:

1. Ade steady-state-spiegel verdubbelt, maar de tijd tot de steady state gelijk blijft
2. Bde steady-state-spiegel gelijk blijft maar de tijd tot het bereiken ervan halveert
3. Cde tijd tot de steady state halveert
4. Dde halfwaardetijd verdubbelt

Why is vincristine labelled "for intravenous use only – fatal if given by other routes"?

1. AAccidental intrathecal injection causes fatal ascending neurotoxicity
2. BIntramuscular injection causes severe and prolonged hypoglycaemia
3. CSubcutaneous injection makes the drug inactive
4. DOral vincristine causes immediate anaphylaxis