Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

Welke bijwerking van morfine verdwijnt bij voortgezet gebruik vrijwel nooit?

  1. ASufheid
  2. BMisselijkheid
  3. CObstipatie
  4. DJeuk
2.Makkelijk

Ciclosporin and tacrolimus are used mainly to:

  1. ATreat bacterial infections after surgery
  2. BPrevent rejection of transplanted organs
  3. CLower high blood cholesterol
  4. DRelieve acute pain after surgery
3.Makkelijk

How long does it usually take for an SSRI to improve mood noticeably?

  1. AAbout six months
  2. BOne or two days
  3. CA few hours
  4. DSeveral weeks
4.Gemiddeld

Why is IV promethazine given with great caution?

  1. AIt is a strong opioid that causes addiction
  2. BIt causes a severe rise in blood pressure when it is given intravenously
  3. CIt causes immediate kidney failure
  4. DIt can cause severe tissue injury if it leaks or enters an artery
5.Gemiddeld

Why is a progestogen added to oestrogen in hormone replacement therapy for a woman who still has her uterus?

  1. ATo lower the risk of blood clots to zero
  2. BTo reduce hot flushes much more than oestrogen alone can
  3. CTo prevent breast cancer completely
  4. DTo protect against endometrial hyperplasia and cancer
6.Gemiddeld

How should oral potassium chloride tablets be taken?

  1. AWith food and plenty of water, swallowed whole if slow-release
  2. BOn an empty stomach with only a small sip of water, then lie down
  3. CLying down straight after the dose
  4. DCrushed and dissolved under the tongue
7.Moeilijk

A teenager took a large overdose of diphenhydramine. He is agitated, hot, flushed and confused, with dry skin, dilated pupils and a full bladder. What is this pattern?

  1. ASerotonin syndrome
  2. BAnticholinergic toxidrome
  3. CCholinergic toxidrome
  4. DOpioid toxidrome
8.Moeilijk

A patient with severe liver cirrhosis needs a benzodiazepine for alcohol withdrawal. Why is lorazepam often chosen instead of diazepam?

  1. ALorazepam is a stronger anticonvulsant than all other benzodiazepines
  2. BLorazepam is excreted unchanged in the urine without any metabolism
  3. CLorazepam does not cause sedation in liver disease
  4. DLorazepam is cleared by simple conjugation and has no active metabolites

Antwoordenblad

  1. 1. C · Obstipatie
  2. 2. B · Prevent rejection of transplanted organs
  3. 3. D · Several weeks
  4. 4. D · It can cause severe tissue injury if it leaks or enters an artery
  5. 5. D · To protect against endometrial hyperplasia and cancer
  6. 6. A · With food and plenty of water, swallowed whole if slow-release
  7. 7. B · Anticholinergic toxidrome
  8. 8. D · Lorazepam is cleared by simple conjugation and has no active metabolites

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