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Naam: ____________________ Datum: ____________
1.Makkelijk
In Addison's disease, fludrocortisone is given to replace which hormone?
AAldosterone
BThyroxine
CCortisol
DAdrenaline
2.Makkelijk
What is a prodrug?
AA drug that is inactive until the body converts it into its active form
BA drug that is given before surgery
CA drug that has passed all clinical trials
DA drug that prevents or reverses the effect of another drug in the body
3.Makkelijk
Benzodiazepinen zoals diazepam werken door het effect van welke neurotransmitter te versterken?
ANoradrenaline
BGlutamaat
CSerotonine
DGABA
4.Gemiddeld
Which patient should usually not use the combined oral contraceptive pill?
AA 30-year-old non-smoker with no medical problems
BA 22-year-old non-smoker with acne
CA 25-year-old woman with heavy periods
DA 38-year-old woman who smokes 20 cigarettes a day
5.Gemiddeld
After naloxone reverses an opioid overdose, why must the patient be watched closely?
ANaloxone often causes severe low blood glucose a few hours after the dose
BNaloxone itself causes respiratory depression at high doses
CNaloxone may wear off before the opioid does, so breathing can slow again
DNaloxone makes the opioid stay longer in the body
6.Gemiddeld
A man takes finasteride. What should be explained about handling the tablets?
APregnant women should not handle crushed or broken tablets
BThe tablets must be crushed before swallowing
CThe tablets must be stored in the fridge
DAnyone can handle the tablets, as they contain no active drug
7.Moeilijk
Een boer die is blootgesteld aan een organofosfaatbestrijdingsmiddel heeft kleine pupillen, sterke speekselvloed, zweten, bronchiale secreties en bradycardie. Wat is het mechanisme?
ABlokkade van GABA-A-receptoren
BRemming van acetylcholinesterase
COvermatige afgifte van noradrenaline
DBlokkade van muscarinereceptoren
8.Moeilijk
Carboprost is a prostaglandin used for postpartum haemorrhage. In which woman should it be avoided?
AA woman with asthma
BA woman who had a vaginal birth
CA woman with iron deficiency anaemia
DA woman who is breastfeeding
Antwoordenblad
1. A · Aldosterone
2. A · A drug that is inactive until the body converts it into its active form
3. D · GABA
4. D · A 38-year-old woman who smokes 20 cigarettes a day
5. C · Naloxone may wear off before the opioid does, so breathing can slow again
6. A · Pregnant women should not handle crushed or broken tablets
7. B · Remming van acetylcholinesterase
8. A · A woman with asthma
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