Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

Which drug is an antidote for methanol or ethylene glycol (antifreeze) poisoning?

  1. AFlumazenil
  2. BFomepizole
  3. CNaloxone
  4. DAtropine
2.Makkelijk

Sumatriptan is used mainly to:

  1. ATreat an acute migraine attack
  2. BTreat high blood pressure
  3. CPrevent epileptic seizures
  4. DRelieve nerve pain from diabetes
3.Makkelijk

Which harmless effect of rifampicin should patients be warned about?

  1. AWhite spots on the teeth
  2. BBlue colouring of the fingernails and lips
  3. COrange-red colouring of urine, sweat and tears
  4. DGreen colouring of the stools
4.Gemiddeld

Which lab tests are monitored in a patient taking carbamazepine?

  1. ASerum amylase and lipase
  2. BThyroid antibodies and cortisol
  3. CFull blood count and serum sodium
  4. DINR and aPTT
5.Gemiddeld

Which signs suggest early lithium toxicity?

  1. AVery high blood pressure and a severe headache
  2. BPinpoint pupils and slow breathing
  3. CHair loss and dark urine only
  4. DDiarrhoea, vomiting, coarse tremor and drowsiness
6.Gemiddeld

A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?

  1. AMake no change, as illness does not affect cortisol needs
  2. BIncrease the dose as instructed (sick-day rules) and seek help if vomiting
  3. CHalve the hydrocortisone to reduce side effects
  4. DStop the hydrocortisone until the fever settles, to let the body recover
7.Moeilijk

A patient on simvastatin is prescribed gemfibrozil. What is the main concern?

  1. ASevere hypoglycaemia
  2. BA sharp rise in LDL cholesterol and triglycerides
  3. CLoss of all lipid-lowering effect
  4. DA much higher risk of myopathy and rhabdomyolysis
8.Moeilijk

A patient who uses insulin is taught sick-day rules. Which statement shows a need for further teaching?

  1. A"I will keep drinking fluids, even if I cannot eat much."
  2. B"I will seek help if I keep vomiting or have ketones."
  3. C"If I am ill and not eating, I will stop my insulin completely."
  4. D"I will check my blood glucose and ketones more often while I am ill."

Antwoordenblad

  1. 1. B · Fomepizole
  2. 2. A · Treat an acute migraine attack
  3. 3. C · Orange-red colouring of urine, sweat and tears
  4. 4. C · Full blood count and serum sodium
  5. 5. D · Diarrhoea, vomiting, coarse tremor and drowsiness
  6. 6. B · Increase the dose as instructed (sick-day rules) and seek help if vomiting
  7. 7. D · A much higher risk of myopathy and rhabdomyolysis
  8. 8. C · "If I am ill and not eating, I will stop my insulin completely."

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