Фармакология: лист заданий с ответами

Donepezil, used in Alzheimer's disease, belongs to which class?

1. ADopamine agonists
2. BAcetylcholinesterase inhibitors
3. CBenzodiazepines
4. DSelective serotonin reuptake inhibitors

Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:

1. ALower the white cell count in leukaemia
2. BIncrease the production of platelets
3. CStop bleeding from wounds
4. DIncrease the production of neutrophils

Какой пероральный препарат обычно является препаратом первой линии при диабете 2 типа?

1. AЛевотироксин
2. BПреднизолон
3. CИнсулин гларгин
4. DМетформин

A patient takes cholestyramine. How should other oral medicines be timed?

1. AMix them into the cholestyramine drink so they are taken together
2. BTake them 1 hour before or several hours after cholestyramine
3. CTiming does not matter, as cholestyramine is not absorbed
4. DTake them all at the same time as cholestyramine

During a rapid infusion of vancomycin, a patient develops flushing and a red rash on the face, neck and upper body. What is the most likely cause and action?

1. AAn infusion reaction; stop or slow the infusion and inform the prescriber
2. BA normal effect; increase the infusion rate to finish sooner
3. CAcute kidney failure; stop all IV fluids and antibiotics at once
4. DA sign that the infection is spreading; give a second dose

A man takes finasteride. What should be explained about handling the tablets?

1. APregnant women should not handle crushed or broken tablets
2. BAnyone can handle the tablets, as they contain no active drug
3. CThe tablets must be stored in the fridge
4. DThe tablets must be crushed before swallowing

Почему бета-блокаторы могут маскировать предупреждающие признаки гипогликемии у людей с диабетом?

1. AОни приглушают адренергические симптомы, например тремор и сердцебиение
2. BОни вызывают лихорадку, скрывающую потливость
3. CОни полностью блокируют выделение инсулина
4. DОни повышают глюкозу, поэтому гипогликемия вообще невозможна

Why is clavulanic acid combined with amoxicillin (co-amoxiclav)?

1. AIt slows the kidney excretion of amoxicillin
2. BIt makes amoxicillin cross the blood–brain barrier more easily
3. CIt inhibits beta-lactamase enzymes that would destroy amoxicillin
4. DIt reduces the risk of penicillin allergy