Фармакология: лист заданий с ответами

Disulfiram is used in alcohol use disorder because it:

1. AReplaces alcohol at its receptors in the brain
2. BRemoves alcohol from the blood faster
3. CCures liver damage caused by alcohol
4. DCauses an unpleasant reaction if alcohol is drunk

Drugs whose names end in "-sartan", such as losartan, belong to which class?

1. AAlpha-1 blockers
2. BLoop diuretics
3. CAngiotensin II receptor blockers
4. DACE inhibitors, which block the converting enzyme

Mesalazine (mesalamine) is used mainly to treat:

1. AGallstones
2. BPeptic ulcer
3. CIrritable bowel syndrome with constipation
4. DUlcerative colitis

A woman taking tamoxifen should report which symptom promptly?

1. AUnusual vaginal bleeding or a painful swollen leg
2. BMild tiredness in the afternoon
3. CMild hot flushes, especially at night, in the first months
4. DSlightly dry skin

A patient takes isoniazid. Which advice is most important?

1. AExpect the urine to turn orange
2. BStop the drug when the cough improves
3. CTake it with antacids to protect the stomach from irritation
4. DAvoid alcohol and report jaundice, dark urine or poor appetite

A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?

1. AAn anticholinergic such as benzatropine (benztropine)
2. BA second dose of haloperidol
3. CNaloxone
4. DDantrolene by mouth to relax the twisted neck muscles

A heparin infusion contains 25,000 units in 500 mL. The order is 1,000 units per hour. What rate should be set on the pump?

1. A50 mL/h
2. B10 mL/h
3. C25 mL/h
4. D20 mL/h

Why is the TPMT enzyme often tested before azathioprine is started?

1. ATPMT testing shows whether the patient has tuberculosis
2. BLow TPMT activity causes toxic levels and marrow suppression
3. CHigh TPMT activity causes an allergic reaction to azathioprine
4. DTPMT is needed to absorb azathioprine from the gut