Фармакология: лист заданий с ответами

Zolpidem is mainly prescribed for:

1. ATreatment of Parkinson's disease
2. BLong-term treatment of depression
3. CPrevention of migraine
4. DShort-term treatment of insomnia

Fibrates such as fenofibrate mainly lower which blood lipid?

1. AHDL cholesterol
2. BLipoprotein(a) only
3. CBile acids
4. DTriglycerides

Oseltamivir is used to treat or prevent which infection?

1. AInfluenza
2. BHIV
3. CHerpes simplex
4. DTuberculosis

Какая фракция лекарства в плазме может достичь рецептора и вызвать эффект?

1. AФракция, связанная с альбумином
2. BФракция, депонированная в эритроцитах
3. CНесвязанная (свободная) фракция
4. DФракция, связанная с глобулинами

Для чего применяют нагрузочную дозу?

1. AЧтобы быстро достичь целевой концентрации в плазме
2. BЧтобы проверить аллергическую реакцию
3. CЧтобы замедлить всасывание препарата
4. DЧтобы уменьшить побочные эффекты в начале лечения

Why are many drugs started at lower doses in older adults?

1. AOlder adults always weigh more than younger adults, so drugs last longer
2. BKidney and liver clearance often decline, and sensitivity to drugs increases
3. COlder adults absorb no drugs from the stomach
4. DLower doses are cheaper for older patients

A patient who takes clonidine stopped it suddenly two days ago. He is now agitated, has a headache and his blood pressure is very high. What is the most likely explanation?

1. ARebound hypertension from abrupt clonidine withdrawal
2. BClonidine toxicity due to slow excretion by the kidneys
3. CNormal variation unrelated to the medication
4. DAn allergic reaction to clonidine

A woman has received a high-dose oxytocin infusion with large volumes of hypotonic fluid for many hours. She now has a headache, confusion and a low serum sodium. What is the most likely cause?

1. ANormal tiredness after a long labour
2. BWater intoxication from the antidiuretic effect of oxytocin
3. CAn allergic reaction to oxytocin causing brain swelling
4. DExcessive salt in the infusion fluid