Фармакология: лист заданий с ответами

Celecoxib selectively inhibits which enzyme?

1. ACyclo-oxygenase-2 (COX-2)
2. BCyclo-oxygenase-1 (COX-1)
3. CLipoxygenase
4. DPhospholipase A2

In hepatic encephalopathy, lactulose is given mainly to:

1. AStop bleeding from varices
2. BLower the blood ammonia level
3. CRaise the blood glucose level
4. DReduce fluid in the abdomen

Какой препарат устраняет действие гепарина?

1. AПротамина сульфат
2. BВитамин K
3. CФлумазенил
4. DНалоксон

A patient is due the first dose of IV cefuroxime. Which question is most important before giving it?

1. A"Have you eaten anything in the last two hours?"
2. B"Do you prefer the drip in your left arm or in your right arm?"
3. C"Have you ever had a reaction to penicillin or another antibiotic?"
4. D"Have you taken paracetamol today?"

A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?

1. AStop the hydrocortisone until the fever settles, to let the body recover
2. BMake no change, as illness does not affect cortisol needs
3. CIncrease the dose as instructed (sick-day rules) and seek help if vomiting
4. DHalve the hydrocortisone to reduce side effects

A man takes finasteride. What should be explained about handling the tablets?

1. APregnant women should not handle crushed or broken tablets
2. BThe tablets must be crushed before swallowing
3. CAnyone can handle the tablets, as they contain no active drug
4. DThe tablets must be stored in the fridge

A patient with myasthenia gravis took extra pyridostigmine doses. She now has increasing weakness, heavy salivation, sweating, small pupils and diarrhoea. What is the most likely cause?

1. AA stroke unrelated to the medication
2. BCholinergic crisis from too much anticholinesterase drug
3. CAn allergic reaction to pyridostigmine
4. DMyasthenic crisis from too little anticholinesterase drug

A nurse gave a patient ten times the prescribed dose of hydromorphone. The patient is currently alert. What is the most appropriate sequence of actions?

1. AMonitor closely, have naloxone ready, inform the prescriber and report
2. BChange the chart so that it shows the correct dose, and continue to monitor
3. CGive another dose later to balance it out
4. DSay nothing because the patient is alert