Фармакология: лист заданий с ответами

Why is HIV treated with a combination of antiretroviral drugs?

1. ATo make the treatment shorter, usually a few weeks
2. BTo suppress the virus and prevent drug resistance
3. CBecause each single drug cures only part of the infection
4. DBecause one drug alone causes no side effects

Fibrates such as fenofibrate mainly lower which blood lipid?

1. ABile acids
2. BTriglycerides
3. CHDL cholesterol
4. DLipoprotein(a) only

Which drug is used as an antidote for cyanide poisoning?

1. ADeferoxamine
2. BHydroxocobalamin
3. CProtamine sulfate
4. DVitamin K

When does oseltamivir give the most benefit in influenza?

1. AAt any time, as the timing makes no difference
2. BOnly after a bacterial pneumonia has developed
3. COnly after symptoms have lasted at least one week
4. DWhen started within 48 hours of the first symptoms

How should a patient store sublingual glyceryl trinitrate (nitroglycerin) tablets?

1. ALoose in a shirt pocket close to the body for quick access
2. BIn a plastic weekly pill box with other tablets
3. CIn the fridge in a damp, open container to keep them fresh and cool
4. DIn the original dark glass bottle, away from heat, light and moisture

Типичные антипсихотики, например галоперидол, действуют в основном путём блокады:

1. AГАМК-A-рецепторов
2. BОбратного захвата серотонина
3. CАцетилхолинэстеразы
4. DДофаминовых D2-рецепторов

A patient on simvastatin is prescribed gemfibrozil. What is the main concern?

1. ASevere hypoglycaemia
2. BA sharp rise in LDL cholesterol and triglycerides
3. CLoss of all lipid-lowering effect
4. DA much higher risk of myopathy and rhabdomyolysis

Why is glibenclamide (glyburide) generally avoided in older adults?

1. AIt is not absorbed in people over 65
2. BIt causes severe weight loss and muscle wasting in older people
3. CIt is long-acting and can cause prolonged, severe hypoglycaemia
4. DIt causes high blood glucose in older adults