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1.Лёгкая
Varenicline helps people stop smoking because it:
AIs a form of nicotine absorbed slowly through the skin
BIs a nicotinic partial agonist that reduces craving and reward
CBlocks dopamine receptors in the brain completely
DMakes cigarettes taste bitter
2.Лёгкая
Disulfiram is used in alcohol use disorder because it:
ACures liver damage caused by alcohol
BCauses an unpleasant reaction if alcohol is drunk
CReplaces alcohol at its receptors in the brain
DRemoves alcohol from the blood faster
3.Лёгкая
Psyllium (ispaghula husk) is which type of laxative?
ABulk-forming
BStool softener
COsmotic
DStimulant
4.Средняя
Why is ketorolac given only for a short course?
AIt quickly loses all its pain-relieving effect because of tolerance
BIt is a strong opioid that causes addiction
CGI bleeding and kidney injury become more likely with longer use
DIt causes respiratory depression after a few days
5.Средняя
Which assessment is most important during IV mannitol therapy?
APlatelet count and signs of bleeding
BLiver enzymes and signs of jaundice
CBlood glucose before meals and signs of hypoglycaemia
DUrine output, electrolytes and signs of fluid overload
6.Средняя
How is adenosine given for supraventricular tachycardia?
AAs a tablet under the tongue
BAs a slow infusion over one hour
CAs a rapid IV push followed by a fast saline flush
DAs an intramuscular injection into the outer thigh muscle
7.Сложная
Why is gentamicin often given once daily instead of in several small doses?
AIt is absorbed slowly from the muscle over 24 hours
BIt has a very long half-life of several days
CIts killing depends on high peak levels, with a post-antibiotic effect
DIts killing depends only on the time the level stays above the MIC
8.Сложная
Why is glibenclamide (glyburide) generally avoided in older adults?
AIt causes high blood glucose in older adults
BIt causes severe weight loss and muscle wasting in older people
CIt is long-acting and can cause prolonged, severe hypoglycaemia
DIt is not absorbed in people over 65
Ответы
1. B · Is a nicotinic partial agonist that reduces craving and reward
2. B · Causes an unpleasant reaction if alcohol is drunk
3. A · Bulk-forming
4. C · GI bleeding and kidney injury become more likely with longer use
5. D · Urine output, electrolytes and signs of fluid overload
6. C · As a rapid IV push followed by a fast saline flush
7. C · Its killing depends on high peak levels, with a post-antibiotic effect
8. C · It is long-acting and can cause prolonged, severe hypoglycaemia
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