Фармакология: лист заданий с ответами

Why do nurses wear chemotherapy-tested gloves and gowns when handling cytotoxic drugs?

1. ATo protect the drug from light
2. BBecause cytotoxic drugs are radioactive and give off radiation
3. CTo keep the drugs warm during the infusion
4. DTo avoid exposure to drugs that may cause cancer or birth defects

Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:

1. AIncrease the production of neutrophils
2. BLower the white cell count in leukaemia
3. CIncrease the production of platelets
4. DStop bleeding from wounds

Which drug is the antidote for paracetamol (acetaminophen) overdose?

1. ANaloxone
2. BVitamin K
3. CFlumazenil
4. DAcetylcysteine

Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?

1. AIt greatly raises the risk of Stevens–Johnson syndrome
2. BThis gene variant speeds up the kidney excretion of carbamazepine
3. CThis gene variant causes carbamazepine to raise blood glucose
4. DThis gene variant makes carbamazepine ineffective

Long-term use of metformin can cause a deficiency of which vitamin?

1. AVitamin K
2. BVitamin B12
3. CVitamin A
4. DVitamin D

In which patient is bupropion contraindicated?

1. AA patient who wants to stop smoking
2. BA patient with a seizure disorder or an eating disorder
3. CA patient with seasonal allergies
4. DA patient with high blood cholesterol and a family history of it

A patient taking digoxin has nausea, yellow-green vision and a dangerous arrhythmia. Which specific treatment can bind the drug?

1. AProtamine sulfate
2. BFlumazenil
3. CDigoxin immune Fab (antibody fragments)
4. DIntravenous vitamin K (phytomenadione) given slowly

A woman has received a high-dose oxytocin infusion with large volumes of hypotonic fluid for many hours. She now has a headache, confusion and a low serum sodium. What is the most likely cause?

1. AAn allergic reaction to oxytocin causing brain swelling
2. BNormal tiredness after a long labour
3. CWater intoxication from the antidiuretic effect of oxytocin
4. DExcessive salt in the infusion fluid