ใบงาน เภสัชวิทยา พร้อมเฉลย

What is enzyme induction?

1. AA drug blocks liver enzymes, so other drugs build up in the blood
2. BA drug speeds up liver enzymes, so other drugs are broken down faster
3. CA drug causes an allergic reaction to enzymes
4. DA drug is converted into an enzyme in the body

อวัยวะใดขับยาที่ละลายน้ำได้และเมแทบอไลต์ส่วนใหญ่ออก?

1. Aตับ
2. Bปอด
3. Cไต
4. Dผิวหนัง

Where is a sublingual tablet placed?

1. AUnder the tongue
2. BBetween the cheek and the gum
3. COn top of the tongue, then chewed
4. DIn the stomach, swallowed with water

อะพิซาแบนและริวารอกซาแบนเป็นยาต้านการแข็งตัวของเลือดที่ยับยั้งโดยตรงต่อ:

1. Aทรอมบิน
2. Bตัวรับ P2Y12 ของเกล็ดเลือด
3. Cแฟคเตอร์ Xa
4. Dวิตามินเคอีพอกไซด์รีดักเทส

Which group of signs suggests opioid withdrawal?

1. AConstipation, itching and a slow heart rate
2. BYawning, runny nose, sweating, dilated pupils and diarrhoea
3. CPinpoint pupils, slow breathing and drowsiness
4. DDry mouth, urinary retention, blurred vision and confusion

Which approach is usually recommended to prevent constipation in a patient on regular opioids?

1. ANo laxative until the patient has not opened the bowels for a week
2. BA stimulant laxative such as senna, often with a stool softener
3. CBulk-forming fibre alone, with fluid intake restricted
4. DAn antidiarrhoeal drug at night to slow the gut

A patient on simvastatin is prescribed gemfibrozil. What is the main concern?

1. AA sharp rise in LDL cholesterol and triglycerides
2. BLoss of all lipid-lowering effect
3. CA much higher risk of myopathy and rhabdomyolysis
4. DSevere hypoglycaemia

A child has a tonic–clonic seizure lasting more than 5 minutes at home and has no IV access. Which drug can be given first by a trained carer or paramedic?

1. AOral paracetamol syrup
2. BOral phenytoin tablets crushed in water
3. CBuccal or intranasal midazolam
4. DIntramuscular morphine