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Ad: ____________________ Tarih: ____________
1.Kolay
How does tamsulosin improve urine flow in benign prostatic hyperplasia?
AIt increases urine production in the kidney
BIt blocks alpha-1 receptors and relaxes prostate smooth muscle
CIt shrinks the prostate gland over months by blocking testosterone
DIt contracts the bladder muscle
2.Kolay
What is drug synergism?
AOne drug cancels out the effect of another drug
BTwo drugs together produce exactly the sum of their separate effects
CTwo drugs together have a greater effect than the sum of each alone
DA drug loses its effect after repeated doses
3.Kolay
What does the combined oral contraceptive pill contain?
AAn oestrogen and a progestogen
BTestosterone and an oestrogen
CA progestogen only
DOxytocin and a progestogen
4.Orta
Varfarin nasıl etki eder?
AK vitaminine bağımlı pıhtılaşma faktörlerinin sentezini engelleyerek
BTrombini doğrudan baskılayarak
CAntitrombini aktive ederek
DCOX-1'in geri dönüşsüz inhibisyonu yoluyla trombosit kümelenmesini engelleyerek
5.Orta
Kalsiyum kanal blokeri amlodipin için hangi yan etki tipiktir?
ABronkospazm
BHiperkalemi
CAyak bileği şişliği
DKuru öksürük
6.Orta
Opioid zehirlenmesinin panzehiri hangi ilaçtır?
ANalokson
BAtropin
CAsetilsistein
DFlumazenil
7.Zor
Why is pethidine (meperidine) avoided in older people and in kidney impairment?
AIt is not absorbed from the gut when kidney function is poor
BIts metabolite norpethidine builds up and can cause seizures
CIt causes severe hypoglycaemia in these groups
DIt has no pain-relieving effect in older people
8.Zor
A patient with diabetic ketoacidosis is about to start an IV insulin infusion. Serum potassium is 3,1 mmol/L (mEq/L). Why is this a concern?
AInsulin moves potassium into cells, so the level can fall dangerously low
BLow potassium makes insulin ineffective, so a higher dose is needed
CPotassium has no link with insulin, so the infusion is started as planned
DInsulin raises potassium further and can cause cardiac arrest, so the infusion is given faster
Cevap anahtarı
1. B · It blocks alpha-1 receptors and relaxes prostate smooth muscle
2. C · Two drugs together have a greater effect than the sum of each alone
3. A · An oestrogen and a progestogen
4. A · K vitaminine bağımlı pıhtılaşma faktörlerinin sentezini engelleyerek
5. C · Ayak bileği şişliği
6. A · Nalokson
7. B · Its metabolite norpethidine builds up and can cause seizures
8. A · Insulin moves potassium into cells, so the level can fall dangerously low
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