Cevaplı Farmakoloji çalışma kâğıdı

Sumatriptan is used mainly to:

1. ATreat high blood pressure
2. BTreat an acute migraine attack
3. CPrevent epileptic seizures
4. DRelieve nerve pain from diabetes

Suda çözünen ilaçların ve metabolitlerinin çoğunu hangi organ atar?

1. ACilt
2. BBöbrek
3. CAkciğer
4. DKaraciğer

How does rasagiline help in Parkinson's disease?

1. AIt is converted directly into dopamine inside brain neurones
2. BIt blocks dopamine receptors in the brain
3. CIt blocks acetylcholine receptors in the gut
4. DIt inhibits MAO-B, so brain dopamine is broken down more slowly

Apiksaban ve rivaroksaban doğrudan neyi inhibe eden antikoagülanlardır?

1. AK vitamini epoksit redüktaz
2. BFaktör Xa
3. CTrombin
4. DTrombosit P2Y12 reseptörü

A patient takes cholestyramine. How should other oral medicines be timed?

1. ATake them 1 hour before or several hours after cholestyramine
2. BTake them all at the same time as cholestyramine
3. CTiming does not matter, as cholestyramine is not absorbed
4. DMix them into the cholestyramine drink so they are taken together

Neostigmin miyastenia gravisde kas gücünü nasıl artırır?

1. AKastaki muskarinik reseptörleri doğrudan uyarır
2. BNöromüsküler kavşaktaki asetilkolin reseptörlerinin sayısını artırır
3. CReseptöre karşı otoantikorları bloke eder
4. DAsetilkolinesterazı inhibe eder, böylece reseptörlere daha fazla asetilkolin ulaşır

A patient with diabetic ketoacidosis is about to start an IV insulin infusion. Serum potassium is 3,1 mmol/L (mEq/L). Why is this a concern?

1. AInsulin raises potassium further and can cause cardiac arrest, so the infusion is given faster
2. BInsulin moves potassium into cells, so the level can fall dangerously low
3. CLow potassium makes insulin ineffective, so a higher dose is needed
4. DPotassium has no link with insulin, so the infusion is started as planned

A malnourished patient with low serum albumin shows nystagmus and unsteady gait. Her total phenytoin level is within range. What is the most likely explanation?

1. AMore phenytoin is unbound when albumin is low, so free levels rise
2. BLow albumin makes phenytoin bind more tightly, so the drug is less active
3. CLow albumin speeds up phenytoin metabolism
4. DThe total level is high, but the laboratory is wrong