Робочий аркуш «Фармакологія» з відповідями

Celecoxib selectively inhibits which enzyme?

1. ALipoxygenase
2. BCyclo-oxygenase-1 (COX-1)
3. CCyclo-oxygenase-2 (COX-2)
4. DPhospholipase A2

Sumatriptan is used mainly to:

1. APrevent epileptic seizures
2. BRelieve nerve pain from diabetes
3. CTreat high blood pressure
4. DTreat an acute migraine attack

Which of these is an extrapyramidal side effect of antipsychotics?

1. AAkathisia (a feeling of inner restlessness)
2. BDry mouth
3. CAgranulocytosis (a very low neutrophil count)
4. DWeight gain

When should a patient take a once-daily proton pump inhibitor such as omeprazole?

1. AAbout 30–60 minutes before the first meal of the day
2. BWith a glass of milk at bedtime, when acid output is highest
3. CStraight after a large evening meal
4. DOnly when heartburn is severe

Іпратропій — бронходилататор, що застосовується при ХОЗЛ. Як він діє?

1. AВін зменшує запалення, як кортикостероїд
2. BВін стимулює бета-2-адренорецептори в дихальних шляхах
3. CВін блокує мускаринові рецептори в гладких м'язах дихальних шляхів
4. DВін блокує лейкотрієнові рецептори

A patient is starting lamotrigine. Which adverse effect should the patient report at once?

1. ASlight tiredness in the afternoon
2. BMild headache on the first day
3. CAny new skin rash
4. DA brief change in taste

A patient taking sertraline starts St John's wort for low mood. What is the main concern?

1. ASerotonin syndrome from combined serotonergic effects
2. BSevere low blood pressure from blocked alpha receptors
3. CA hypertensive crisis from tyramine
4. DBleeding from vitamin K deficiency

Why may omeprazole be avoided in a patient taking clopidogrel?

1. AIt speeds up kidney excretion of clopidogrel
2. BIt binds clopidogrel in the stomach and makes it insoluble
3. CIt increases clopidogrel absorption from the gut and causes bleeding
4. DIt inhibits CYP2C19, so less clopidogrel is converted to its active form