Робочий аркуш «Фармакологія» з відповідями

What is drug synergism?

1. ATwo drugs together have a greater effect than the sum of each alone
2. BOne drug cancels out the effect of another drug
3. CTwo drugs together produce exactly the sum of their separate effects
4. DA drug loses its effect after repeated doses

After chemotherapy, what is the "nadir"?

1. AThe point when blood cell counts are at their lowest
2. BThe point when the tumour is at its smallest after treatment
3. CThe day the drug is given
4. DThe time when nausea is worst

Which drug is the antidote for magnesium sulfate toxicity?

1. APotassium chloride
2. BProtamine sulfate
3. CNaloxone
4. DCalcium gluconate

Яка ознака типова для опіоїдної токсичності?

1. AШироко розширені зіниці
2. BЧасте, глибоке дихання
3. CВисока температура тіла
4. DТочкові зіниці

An Rh-negative mother gives birth to an Rh-positive baby. When is anti-D immunoglobulin usually given?

1. AIt is not needed if the baby is Rh-positive
2. BWithin 72 hours after the birth
3. CAt least two weeks after the birth
4. DOnly at the start of the next pregnancy

Before starting a TNF-alpha inhibitor such as adalimumab, which test is required?

1. AAn echocardiogram in every patient
2. BScreening for latent tuberculosis
3. CA bone density scan
4. DA glucose tolerance test

A malnourished patient with low serum albumin shows nystagmus and unsteady gait. Her total phenytoin level is within range. What is the most likely explanation?

1. AThe total level is high, but the laboratory is wrong
2. BLow albumin speeds up phenytoin metabolism
3. CLow albumin makes phenytoin bind more tightly, so the drug is less active
4. DMore phenytoin is unbound when albumin is low, so free levels rise

Ten days after chemotherapy, a patient has a temperature of 38,5 °C (101,3 °F) but says she feels fine. What should happen?

1. AParacetamol at home and review at the next routine clinic visit
2. BUrgent cultures and IV broad-spectrum antibiotics without delay
3. CStart oral antibiotics only if a rash develops
4. DWait 48 hours to see whether the fever settles