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Ім’я: ____________________ Дата: ____________
1.Легка
Why is anti-D immunoglobulin given to an Rh-negative mother?
ATo make her own blood group Rh-positive before the next pregnancy
BTo speed up labour
CTo treat anaemia in the newborn
DTo stop her forming anti-D antibodies against Rh-positive fetal cells
2.Легка
Which intramuscular site is recommended for infants?
AVastus lateralis (outer thigh)
BDeltoid
CVentral forearm
DDorsogluteal (upper outer buttock)
3.Легка
Lithium is used mainly to treat which condition?
ABipolar disorder
BGeneralised anxiety disorder
CSchizophrenia with no mood symptoms
DAttention deficit hyperactivity disorder
4.Середня
Як інгібітори SGLT2, як-от емпагліфлозин, знижують глюкозу крові?
AВони змушують печінку запасати більше глікогену
BВони сповільнюють спорожнення шлунка
CВони збільшують втрату глюкози із сечею
DВони стимулюють вивільнення інсуліну з бета-клітин
5.Середня
Why is a spacer recommended with a metered-dose inhaler?
AIt doubles the dose of drug released by each puff of the inhaler
BIt turns the inhaler into a nebuliser
CIt removes the need to shake the inhaler
DMore drug reaches the lungs and less stays in the mouth
6.Середня
Why is simvastatin traditionally taken in the evening?
AIt is short-acting, and cholesterol synthesis peaks at night
BIt is inactivated by sunlight during the day
CIt must be taken with the largest meal of the day
DIt causes too much drowsiness to be taken in the morning
7.Складна
Why may omeprazole be avoided in a patient taking clopidogrel?
AIt increases clopidogrel absorption from the gut and causes bleeding
BIt inhibits CYP2C19, so less clopidogrel is converted to its active form
CIt binds clopidogrel in the stomach and makes it insoluble
DIt speeds up kidney excretion of clopidogrel
8.Складна
A patient with myasthenia gravis took extra pyridostigmine doses. She now has increasing weakness, heavy salivation, sweating, small pupils and diarrhoea. What is the most likely cause?
ACholinergic crisis from too much anticholinesterase drug
BA stroke unrelated to the medication
CAn allergic reaction to pyridostigmine
DMyasthenic crisis from too little anticholinesterase drug
Ключ відповідей
1. D · To stop her forming anti-D antibodies against Rh-positive fetal cells
2. A · Vastus lateralis (outer thigh)
3. A · Bipolar disorder
4. C · Вони збільшують втрату глюкози із сечею
5. D · More drug reaches the lungs and less stays in the mouth
6. A · It is short-acting, and cholesterol synthesis peaks at night
7. B · It inhibits CYP2C19, so less clopidogrel is converted to its active form
8. A · Cholinergic crisis from too much anticholinesterase drug
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