Practice exercise (made-up values, not clinical guidance). A patient receives aminophylline as a constant IV infusion without a loading dose. The half-life is 9 h. What percentage f of the steady-state level has been reached after 13.5 h?
Practice exercise (made-up values, not clinical guidance). A patient receives lidocaine as a constant IV infusion without a loading dose. The half-life is 1.5 h. What percentage f of the steady-state level has been reached after 2.25 h?
Practice exercise (made-up values, not clinical guidance). A 52 kg patient receives a theophylline infusion. The clearance is 0.035 L/kg/h. What infusion rate R in mg/h gives a steady-state level of 12 mg/L?
Practice exercise (made-up values, not clinical guidance). After an IV dose of gentamicin, the level is 10 mg/L at 1 h and 3 mg/L at 7 h. Assume first-order elimination. Find the half-life t½.
Practice exercise (made-up values, not clinical guidance). A 99 kg patient on regular tobramycin doses is at steady state. The target is a peak of 8 mg/L and a trough of 1 mg/L, and the volume of distribution is 0.3 L/kg. Assuming rapid IV doses, what dose D raises the level from the trough to the peak?
Practice exercise (made-up values, not clinical guidance). An 81 kg patient takes oral theophylline (F = 1) every 8 h. The clearance is 0.035 L/kg/h. What dose D in mg gives an average steady-state level of 10 mg/L?
Full step-by-step solutions: practise this topic on examproblems.com.