Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the positive predictive value PPV as a percentage. Round to one decimal place.
Evidence-based practice statistics worksheet with answers
Practice exercise (made-up values, not clinical guidance). A town has 3000 inhabitants. At the start of a year, 46 of them have a chronic disease. During the year, 21 more people are newly diagnosed (assume nobody moves away or dies). Find the point prevalence P at the start of the year per 1000 inhabitants. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). In a randomised trial, 220 patients received a new treatment and 500 received the control treatment. The table shows how many in each group had the outcome (an unwanted event such as a stroke). Find the number needed to treat NNT to prevent one event. Round up to a whole number of patients.
Practice exercise (made-up values, not clinical guidance). In a cohort study, exposed people contributed 7100 person-years with 142 new cases, and unexposed people 6700 person-years with 34 new cases. Find the incidence rate ratio IRR (exposed versus unexposed). Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). A screening test has a sensitivity of 92% and a specificity of 89%. It is used in a population where the prevalence is 20%. Find the positive predictive value PPV as a percentage. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). 10 000 people are screened with a test of sensitivity 87% and specificity 92%. The prevalence of the disease is 24%. How many people with the disease are missed by the test (false negatives, FN)?
Answer key
- 1. PPV = 82.4 %
- 2. P = 15.3 per 1000
- 3. NNT = 31
- 4. IRR = 3.94
- 5. PPV = 67.6 %
- 6. FN = 312
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