1.Easy
In primary hypothyroidism, what is the usual TSH result?
- AHigh
- BUndetectable
- CLow
- DNormal
2.Easy
Which fluid is usually given first in diabetic ketoacidosis?
- AIV 50% glucose solution
- BIV 0.9% sodium chloride
- CIV sterile water for injection
- DOral sugary drinks and water
3.Easy
What is acromegaly?
- AToo little growth hormone in a child
- BToo little thyroid hormone in an adult
- CToo much cortisol from the adrenal glands
- DToo much growth hormone in an adult
4.Medium
A patient taking dapagliflozin (an SGLT2 inhibitor) is vomiting, with blood ketones of 4.5 mmol/L but a glucose of only 11 mmol/L. What should be suspected?
- AHypoglycaemia caused by the vomiting
- BEuglycaemic diabetic ketoacidosis
- CHyperosmolar hyperglycaemic state
- DA normal side effect needing no action
5.Medium
Which group of drugs is a well-known cause of SIADH and hyponatraemia, especially in older people?
- ASSRI antidepressants
- BProton pump inhibitors
- CPenicillin antibiotics
- DBulk-forming laxatives
6.Medium
A patient has just started haemodialysis. What usually happens to their protein needs?
- AThey increase, because dialysis removes amino acids
- BThey fall to almost zero to rest the kidneys
- CThey stay exactly the same as they were before dialysis
- DProtein must be replaced only by IV infusion
7.Hard
A patient with gastroparesis has hypos soon after their meal-time insulin, then high glucose several hours later. What is the best explanation?
- AThe patient is secretly eating sweets between meals
- BThe insulin has gone off and needs replacing
- CFood is absorbed slowly, so the insulin peaks before the glucose rises
- DThe meter gives false results for several hours after every meal
8.Hard
A patient with a severe head injury does not open the eyes, and in response to pain the arms extend and rotate inwards with the legs extended. What does this indicate?
- AFlexor (decorticate) posturing, a sign of mild cortical injury
- BA normal withdrawal response to a painful stimulus
- CExtensor (decerebrate) posturing: severe brainstem injury
- DA focal seizure that will stop without any treatment
Answer key
- 1. A · High
- 2. B · IV 0.9% sodium chloride
- 3. D · Too much growth hormone in an adult
- 4. B · Euglycaemic diabetic ketoacidosis
- 5. A · SSRI antidepressants
- 6. A · They increase, because dialysis removes amino acids
- 7. C · Food is absorbed slowly, so the insulin peaks before the glucose rises
- 8. C · Extensor (decerebrate) posturing: severe brainstem injury
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