1.Easy
What is acromegaly?
- AToo much growth hormone in an adult
- BToo much cortisol from the adrenal glands
- CToo little growth hormone in a child
- DToo little thyroid hormone in an adult
2.Easy
Which symptoms are typical of uraemia in advanced kidney disease?
- ASevere flank pain with visible blood in the urine
- BExcess thirst with a very high glucose
- CItching, nausea, tiredness and poor appetite
- DHeat intolerance, tremor and weight loss
3.Easy
Which statement about metformin is correct?
- AIt works by making the pancreas release a lot more insulin
- BUsed on its own, it rarely causes hypoglycaemia
- CIt is the usual first treatment for type 1 diabetes in adults
- DIt is given by injection into the abdomen once a week
4.Medium
Why should long-term steroid treatment not be stopped suddenly?
- AThe steroids build up and become toxic after they are stopped
- BThe suppressed adrenal glands cannot make enough cortisol at once
- CStopping causes the blood glucose to fall sharply
- DStopping suddenly makes the bones grow too quickly and then fracture
5.Medium
A patient with type 1 diabetes has gastroenteritis and cannot eat. Which sick-day advice is correct?
- AKeep taking basal insulin and check glucose and ketones more often
- BCheck glucose once a day only and rest in bed until better
- CStop all insulin until normal eating restarts
- DAvoid drinking fluids to reduce the vomiting
6.Medium
Which headache feature most suggests raised intracranial pressure from a brain tumour?
- AWorse on waking and on coughing, with vomiting
- BA tight band across the forehead that eases with rest
- CBetter in the morning and worse with stress
- DOnly present after reading for a long time
7.Hard
A patient with AKI has a low urine sodium and concentrated urine. What does this suggest?
- ADiabetes insipidus, with too little ADH
- BA post-renal blockage, with urine backed up
- CA pre-renal cause, with kidneys holding salt and water
- DAcute tubular necrosis, with damaged and leaking tubules
8.Hard
A patient with a brain tumour on high-dose dexamethasone has a capillary glucose of 16 mmol/L (288 mg/dL). They have no history of diabetes. What is the best explanation?
- AA sign that the brain tumour has now spread to the pancreas
- BNormal for this patient, so no action is needed
- CSteroid-induced hyperglycaemia, which needs monitoring and treatment
- DA lab error, because steroids lower blood glucose
Answer key
- 1. A · Too much growth hormone in an adult
- 2. C · Itching, nausea, tiredness and poor appetite
- 3. B · Used on its own, it rarely causes hypoglycaemia
- 4. B · The suppressed adrenal glands cannot make enough cortisol at once
- 5. A · Keep taking basal insulin and check glucose and ketones more often
- 6. A · Worse on waking and on coughing, with vomiting
- 7. C · A pre-renal cause, with kidneys holding salt and water
- 8. C · Steroid-induced hyperglycaemia, which needs monitoring and treatment
Full step-by-step solutions: practise this topic on examproblems.com.