1.Easy
What is a yeast?
- AA multicellular parasite
- BA type of spiral bacterium
- CA small virus
- DA single-celled fungus
2.Easy
What is meant by the normal flora (microbiota) of the body?
- ABacteria that always cause mild infections
- BMicroorganisms found only in sick patients
- CThe white blood cells in healthy tissue
- DMicroorganisms that normally live on or in the body without causing disease
3.Easy
Edward Jenner is known for developing vaccination against which disease?
- ASmallpox
- BTuberculosis
- CPolio
- DRabies
4.Medium
What is the main difference between innate and adaptive immunity?
- AAdaptive immunity is specific and forms memory; innate immunity does not
- BInnate immunity uses antibodies and forms memory; adaptive immunity does not
- CAdaptive immunity acts within minutes of infection
- DInnate immunity develops only after vaccination
5.Medium
What is the main virulence factor of Streptococcus pneumoniae, and the target of its vaccines?
- AIts flagella
- BIts cholera-like toxin
- CIts endospores
- DIts polysaccharide capsule
6.Medium
MRSA is resistant to methicillin because it has:
- AA polysaccharide capsule that blocks the entry of all beta-lactams
- BNo cell wall at all
- CAn efflux pump for every antibiotic
- DAn altered penicillin-binding protein (PBP2a)
7.Hard
A patient with suspected infectious pulmonary tuberculosis is admitted. Which precautions are needed?
- AAirborne precautions, ideally a negative-pressure room and respirator masks for staff
- BDroplet precautions with a surgical mask, and only within one metre
- CContact precautions only, with gloves and an apron
- DNo special precautions, because TB spreads only by blood
8.Hard
How do high-risk HPV types contribute to cervical cancer?
- AThe virus kills cells so quickly that they are replaced by cancer cells
- BThe virus destroys CD4 T cells in the cervix
- CViral E6 and E7 proteins inactivate the tumour suppressors p53 and Rb
- DThe virus produces an endotoxin that damages DNA
Answer key
- 1. D · A single-celled fungus
- 2. D · Microorganisms that normally live on or in the body without causing disease
- 3. A · Smallpox
- 4. A · Adaptive immunity is specific and forms memory; innate immunity does not
- 5. D · Its polysaccharide capsule
- 6. D · An altered penicillin-binding protein (PBP2a)
- 7. A · Airborne precautions, ideally a negative-pressure room and respirator masks for staff
- 8. C · Viral E6 and E7 proteins inactivate the tumour suppressors p53 and Rb
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