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Name: ____________________ Date: ____________
1.Easy
Which description fits insulin glargine?
AA rapid-acting insulin given with each meal
BAn oral tablet that makes the pancreas release insulin
CA long-acting basal insulin with no marked peak
DAn intermediate-acting cloudy insulin with a clear peak
2.Easy
In the United States, what is a "boxed warning" (black box warning) on a drug label?
AA note that the drug is available without prescription
BThe strongest FDA warning about a serious or life-threatening risk
CA sign that the drug must be stored in a dark box
DA label showing that the drug is a controlled substance with abuse potential
3.Easy
Why is HIV treated with a combination of antiretroviral drugs?
ATo make the treatment shorter, usually a few weeks
BBecause one drug alone causes no side effects
CTo suppress the virus and prevent drug resistance
DBecause each single drug cures only part of the infection
4.Medium
Sumatriptan is contraindicated in which patient?
AA patient with iron deficiency anaemia
BA patient with mild asthma
CA patient with coronary artery disease
DA patient with a recent ankle sprain
5.Medium
How should a patient store sublingual glyceryl trinitrate (nitroglycerin) tablets?
AIn the original dark glass bottle, away from heat, light and moisture
BIn the fridge in a damp, open container to keep them fresh and cool
CLoose in a shirt pocket close to the body for quick access
DIn a plastic weekly pill box with other tablets
6.Medium
Why do patients taking clozapine need regular blood counts?
AIt raises the platelet count dangerously
BIt can cause agranulocytosis
CIt changes the blood group
DIt often causes iron-deficiency anaemia
7.Hard
A patient has an anaphylactic reaction to the first dose of amoxicillin. How is this adverse reaction classified in the common A/B system?
AType A, because it is dose-related and predictable from the drug's pharmacology
BType B, because it is unpredictable and unrelated to the drug's normal action
CType A, because the dose was too high
DType B, because it occurs only after long-term use
8.Hard
A patient on heparin for 7 days has a platelet count that has fallen by more than half, and a new leg vein thrombosis. What is the most likely cause and the key action?
AVitamin K deficiency; give vitamin K and continue heparin
BHeparin-induced thrombocytopenia; stop all heparin
CWarfarin skin necrosis; switch from heparin to warfarin at once
DNormal dilution of platelets; continue and recheck in a week
Answer key
1. C · A long-acting basal insulin with no marked peak
2. B · The strongest FDA warning about a serious or life-threatening risk
3. C · To suppress the virus and prevent drug resistance
4. C · A patient with coronary artery disease
5. A · In the original dark glass bottle, away from heat, light and moisture
6. B · It can cause agranulocytosis
7. B · Type B, because it is unpredictable and unrelated to the drug's normal action
8. B · Heparin-induced thrombocytopenia; stop all heparin
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