1.Easy
Fluconazole is used to treat infections caused by:
- AViruses such as influenza
- BGram-negative bacteria
- CParasites such as malaria
- DFungi such as Candida
2.Easy
Mesalazine (mesalamine) is used mainly to treat:
- APeptic ulcer
- BGallstones
- CIrritable bowel syndrome with constipation
- DUlcerative colitis
3.Easy
Which signs are typical of hypoglycaemia?
- AFruity breath with deep, rapid breathing
- BSweating, shakiness, a fast heart rate and confusion
- CThirst, frequent urination and warm, dry, flushed skin
- DA slow pulse, constipation and weight gain
4.Medium
Which patient should usually not use the combined oral contraceptive pill?
- AA 25-year-old woman with heavy periods
- BA 22-year-old non-smoker with acne
- CA 30-year-old non-smoker with no medical problems
- DA 38-year-old woman who smokes 20 cigarettes a day
5.Medium
Which serious but rare adverse effect of statins should patients report straight away?
- AAnkle swelling
- BUnexplained muscle pain or weakness
- CA metallic taste
- DA dry cough
6.Medium
A patient with diabetes is sweaty and shaky. Blood glucose is 3.0 mmol/L (54 mg/dL). The patient is awake and can swallow. What should the nurse do first?
- AGive 15–20 g of fast-acting carbohydrate, such as juice
- BGive a large meal high in fat and protein to keep glucose up for longer
- CGive intramuscular glucagon at once
- DGive the next scheduled dose of insulin
7.Hard
The clearance of a drug falls to half because of kidney failure, while its volume of distribution stays the same. What happens to its half-life?
- AIt increases fourfold
- BIt stays the same
- CIt halves
- DIt doubles
8.Hard
A patient on weekly methotrexate is prescribed trimethoprim for a urinary infection. What is the main risk?
- ASevere hypertension from the combination
- BBone marrow suppression, because both drugs inhibit folate metabolism
- CLoss of antibiotic effect because methotrexate binds trimethoprim
- DHypoglycaemia from reduced liver glucose output
Answer key
- 1. D · Fungi such as Candida
- 2. D · Ulcerative colitis
- 3. B · Sweating, shakiness, a fast heart rate and confusion
- 4. D · A 38-year-old woman who smokes 20 cigarettes a day
- 5. B · Unexplained muscle pain or weakness
- 6. A · Give 15–20 g of fast-acting carbohydrate, such as juice
- 7. D · It doubles
- 8. B · Bone marrow suppression, because both drugs inhibit folate metabolism
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