1.Easy
Drugs whose names end in "-pril", such as lisinopril, belong to which class?
- ABeta blockers
- BCalcium channel blockers
- CACE inhibitors
- DAngiotensin II receptor blockers
2.Easy
Which drug can be used in beta blocker overdose because it raises heart rate through a non-adrenergic pathway?
- ANaloxone
- BFlumazenil
- CInsulin
- DGlucagon
3.Easy
In the United States, what does a Schedule II controlled substance mean?
- AA drug with no accepted medical use and a high potential for abuse
- BA drug available freely over the counter
- CA drug with almost no risk of abuse
- DA drug with accepted medical use but a high risk of abuse
4.Medium
After naloxone reverses an opioid overdose, why must the patient be watched closely?
- ANaloxone often causes severe low blood glucose a few hours after the dose
- BNaloxone makes the opioid stay longer in the body
- CNaloxone may wear off before the opioid does, so breathing can slow again
- DNaloxone itself causes respiratory depression at high doses
5.Medium
A patient takes theophylline for COPD. Which advice is most important?
- ATake extra doses when short of breath
- BLimit coffee, tea and cola, because caffeine adds to the side effects
- CDrink plenty of grapefruit juice each morning to improve absorption
- DAvoid potassium-rich foods such as bananas
6.Medium
How should a patient store sublingual glyceryl trinitrate (nitroglycerin) tablets?
- ALoose in a shirt pocket close to the body for quick access
- BIn the original dark glass bottle, away from heat, light and moisture
- CIn a plastic weekly pill box with other tablets
- DIn the fridge in a damp, open container to keep them fresh and cool
7.Hard
A patient taking azathioprine is prescribed allopurinol for gout. What is the main danger?
- ASevere bone marrow suppression, because azathioprine breakdown is reduced
- BSevere hypertension from the combination
- CLiver enzyme induction, making azathioprine ineffective
- DGout becomes worse because allopurinol is inactivated by azathioprine
8.Hard
A man taking doxazosin for hypertension starts sildenafil for erectile dysfunction. What is the main risk?
- ASevere hypertension and a pounding headache
- BBronchospasm
- CSymptomatic low blood pressure and fainting
- DHyperkalaemia
Answer key
- 1. C · ACE inhibitors
- 2. D · Glucagon
- 3. D · A drug with accepted medical use but a high risk of abuse
- 4. C · Naloxone may wear off before the opioid does, so breathing can slow again
- 5. B · Limit coffee, tea and cola, because caffeine adds to the side effects
- 6. B · In the original dark glass bottle, away from heat, light and moisture
- 7. A · Severe bone marrow suppression, because azathioprine breakdown is reduced
- 8. C · Symptomatic low blood pressure and fainting
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