Pharmacology worksheet with answers

After chemotherapy, what is the "nadir"?

1. AThe point when the tumour is at its smallest after treatment
2. BThe time when nausea is worst
3. CThe day the drug is given
4. DThe point when blood cell counts are at their lowest

Which oral drug is commonly the first-line medicine for type 2 diabetes?

1. APrednisolone
2. BLevothyroxine
3. CMetformin
4. DInsulin glargine

Sertraline, an antidepressant, increases the level of which neurotransmitter in the synapse?

1. ADopamine
2. BAcetylcholine
3. CSerotonin
4. DGABA

How should oral potassium chloride tablets be taken?

1. AWith food and plenty of water, swallowed whole if slow-release
2. BOn an empty stomach with only a small sip of water, then lie down
3. CCrushed and dissolved under the tongue
4. DLying down straight after the dose

Why do NSAIDs such as ibuprofen increase the risk of stomach ulcers?

1. AThey directly dissolve the mucus layer
2. BThey increase the number of Helicobacter pylori bacteria in the stomach
3. CThey reduce protective prostaglandins in the stomach lining
4. DThey raise the pH of gastric acid

When does oseltamivir give the most benefit in influenza?

1. AWhen started within 48 hours of the first symptoms
2. BAt any time, as the timing makes no difference
3. COnly after a bacterial pneumonia has developed
4. DOnly after symptoms have lasted at least one week

A man taking spironolactone for heart failure develops painful breast enlargement. Which change may be considered?

1. ASwitching to potassium chloride tablets
2. BAdding testosterone injections
3. CDoubling the spironolactone dose to overcome the side effect
4. DSwitching to eplerenone, which has fewer anti-androgen effects

A patient who used cocaine has chest pain, agitation, a high temperature, sweating, tachycardia and dilated pupils. Which drug class is commonly first-line for the agitation and sympathetic overactivity?

1. AAnticholinergic drugs
2. BBenzodiazepines
3. CAntihistamines
4. DOpioid antagonists