Pharmacology worksheet with answers

Which signs are typical of hypoglycaemia?

1. AA slow pulse, constipation and weight gain
2. BSweating, shakiness, a fast heart rate and confusion
3. CFruity breath with deep, rapid breathing
4. DThirst, frequent urination and warm, dry, flushed skin

Which drug is the first-line treatment for anaphylaxis?

1. AInhaled salbutamol
2. BOral prednisolone
3. CIntramuscular adrenaline
4. DOral antihistamine

Penicillins kill bacteria by interfering with:

1. AFolic acid synthesis
2. BDNA replication
3. CCell wall synthesis
4. DProtein synthesis at the ribosome

In which patient is bupropion contraindicated?

1. AA patient with high blood cholesterol and a family history of it
2. BA patient with seasonal allergies
3. CA patient who wants to stop smoking
4. DA patient with a seizure disorder or an eating disorder

Apixaban and rivaroxaban are anticoagulants that directly inhibit:

1. AVitamin K epoxide reductase
2. BFactor Xa
3. CThe platelet P2Y12 receptor
4. DThrombin

How does neostigmine improve muscle strength in myasthenia gravis?

1. AIt blocks the autoantibodies against the receptor
2. BIt directly stimulates muscarinic receptors in muscle
3. CIt increases the number of acetylcholine receptors at the neuromuscular junction
4. DIt inhibits acetylcholinesterase so more acetylcholine reaches the receptors

Why may omeprazole be avoided in a patient taking clopidogrel?

1. AIt inhibits CYP2C19, so less clopidogrel is converted to its active form
2. BIt increases clopidogrel absorption from the gut and causes bleeding
3. CIt speeds up kidney excretion of clopidogrel
4. DIt binds clopidogrel in the stomach and makes it insoluble

Which statement correctly contrasts donepezil and memantine in Alzheimer's disease?

1. ADonepezil blocks NMDA receptors; memantine inhibits acetylcholinesterase
2. BBoth drugs are dopamine agonists that differ only in their half-lives
3. CDonepezil inhibits cholinesterase; memantine blocks NMDA receptors
4. DBoth drugs remove amyloid plaques from the brain